Polycystic Ovary Syndrome
Conditions
Keywords
PCOS, Inflammation, Body Composition
Brief summary
Polycystic ovary syndrome (PCOS) is a common endocrine disorder in premenopausal women. PCOS is characterized by increase levels of testosterone, unwanted hair growth, adiposity, irregular menstrual cycle, and infertility. PCOS is associated with diabetes mellitus and cardiovascular diseases. Women with PCOS are reported to have increased levels of stress hormones, which may be associated with decreased quality of life. Increased testosterone levels in women may decrease the risk of osteoporosis. The aim of the present study is to measure levels of stress hormones in urine and describe quality of life using questionnaires. In addition we aim to characterize body composition and bone architecture using DXA and ExtremeCT. As part of the project, a Biobank with fasting blood samples from participants is established.
Interventions
None listed
Sponsors
Odense University Hospital
Study design
Observational model
OTHER
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 45 Years
Healthy volunteers
Yes
Inclusion criteria
* PCOS
Exclusion criteria
* pregnancy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| bone mass density (BMD) | baseline | BMD measured by DXA scans and ExtremeCT scans. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Stress hormones | Baseline | Measurement of cortisol and steroid metabolites in 24 hour urine samples |
Countries
Denmark
Contacts
Primary ContactMarianne Andersen, DMSci
Outcome results
None listed