Atherosclerosis, Plaque, Atherosclerotic
Conditions
Keywords
Military Active Duty Enlisted, Atherosclerosis, Coronary Artery Calcium (CAC), Cardiovascular, CAC Score, Framingham Score, CT Scan
Brief summary
Hypothesis: Enlisted military members with 10 or more years of service and at least one cardiovascular risk factor will demonstrate a higher risk of future cardiac events as assessed by coronary artery calcium (CAC) scoring than the risk calculated by the Framingham Risk Score.
Detailed description
While the military is making strides towards improving the health and habits of service members, there are many aspects of the military culture that negatively affect the cardiovascular health of military members. Smoking/tobacco use, poor eating habits with Meals Ready-to-eat (MRE) and ready access to fast food establishments on base, inconsistent exercise, the socioeconomic status of enlisted members and the stress of deployment are all factors that contribute to increased risk of cardiovascular disease during military service. Currently the calculation of a patient's Framingham risk score is the most commonly used method of calculating a patient's cardiovascular risk, and this calculation is based on age, smoking history, blood pressure, and lab values and compares it to a general population's risk. By the use of a cardiac computerized topography (CT) scan, a Coronary Artery Calcium (CAC) score can be calculated and used to estimate the degree of atherosclerosis already present in each patient's coronary arteries, and thus establishing their risk of future cardiovascular events. CAC scoring is a more patient-specific way of identifying cardiovascular risk. The purpose of this study is to assess the prevalence of atherosclerosis in enlisted military members with at least 10 years of service and one or more cardiovascular risk factor and to determine if their risk of a cardiovascular event is higher than predicted by the Framingham score. If CAC scoring is demonstrated to be more accurate, particularly if it is more likely to detect risk, it may be used in the future to better risk stratify this population of the military. The CAC results in patients could also be a motivating factor to create changes in the military culture to attempt to mitigate these risks and create a healthier fighting force.
Interventions
None listed
Sponsors
David Grant U.S. Air Force Medical Center
Study design
Observational model
OTHER
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
35 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
Active Duty Military Members with at least 10 years of service Enlisted Rank Males 35 years and older OR Females 45 years and older (please note the age difference is due to the fact that female plaque formation with calcification has been shown to lag that of males by about 10 years) One or More of the Following Risk Factors: Smoker - at least 5 pack years in the past 5 years (pack year = number of packs per day number of years of smoking) Diabetic (Fasting glucose of \>125 mg/dL on two or more blood draws, or Random Blood Glucose of \>200 mg/dL on a single blood draw, or Hemoglobin A1C \>6.5%, or previous diagnosis of diabetes listed in the subject's medical record) or Pre-diabetic (Fasting glucose \>100 on two or more blood draws or Hgb A1C 5.7-6.4) Hypertension (Systolic BP \> 140 or Diastolic BP \>90 or on blood pressure medications or diagnosis of hypertension in medical record) Waist Circumference \> 40 inches for males or \>35 inches for females Hyperlipidemia (LDL\>130, HDL\<40 for males, HDL \<50 for females, Triglycerides \>200, on lipid lowering medications and/or diagnosis of hyperlipidemia in medical record)
Exclusion criteria
Males \<35 years old Women \<45 years old (please note the age difference is due to the fact that female plaque formation with calcification has been shown to lag that of males by about 10 years) Officer Rank - officers are excluded as we are looking at the enlisted culture in the military. History of any of the following: Coronary Artery Disease (CAD) Coronary Artery Bypass Grafting (CABG) Myocardial Infarction (MI) Percutaneous Intervention/Stent Placement (PCI) Angina Radiotherapy (external beam, brachytherapy, radiopharmaceutical) Under the care of any of the following types of providers in the past 12 months (As these subjects are at greater risk of having had significant radiation exposure to the chest over the past 12 months): Radiation/Medical Oncologist Interventional Radiologist Cardiologist Cardiothoracic Surgeon Vascular Surgeon Females who think they may be pregnant Pregnant females
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Prevalence of Atherosclerosis | within 10 days of CT scan | Percent of active duty enlisted military members with 10 or more years of military service determined to have a prevalence of atherosclerosis based on CAC risk category. The CAC risk category (scale), is derived from the CAC score (i.e., an estimate of the degree of atherosclerosis present in each participant's coronary arteries, reported as a number), and percentage by age to establish risk of future CV events. There are 5 risk categories: Low risk = CAC of 0 and no cardiovascular (CV) risk factors, Low - Moderate risk = CAC of 0 with CV risk factors, Moderate - High risk: CAC 1-100 and percentile for age \<75%, High risk = CAC 100-399 or percentile for age \>75%, Very high risk = CAC \>100 and percentile for age \>90% or CAC \>400. Low risk is the best outcome, and very high risk is the worst. |
| Rate of Reclassification | within 10 days of CT scan | Percent/Number of subject that were reclassified from FRS to CAC risk category using CAC scores. The CAC risk category (scale) = CAC score (estimated degree of calcium in coronary arteries, a number) + percentage by age to establish risks of future CV events. There are 5 risk categories: low, low - moderate, moderate - high, very high. The Framingham risk category (scale) = FRS to estimate the risk of a CV event over the next 10 years. The FRS uses age, systolic blood pressure, high-density lipoprotein (HDL) cholesterol level, total cholesterol level, and smoking status to create a score that is converted into a 10-year CV disease risk % that correlates into a risk category: low, moderate, moderate - high risk, very high. For both scales, low is the best and very high is the worst outcome |
| Compare FRS to the CAC - At Least One Additional Risk Factor | within 10 days of CT scan | Compare FRS risk category to CAC risk category for enlisted subjects with at least 10 years of service and at least one additional CV risk factor to determine how well the results correlate with one another using the Spearman's Rank Correlation Coefficient. The CAC risk category (scale) = CAC score (estimated degree of calcium in coronary arteries, a number) + percentage by age to establish risks of future CV events. There are 5 risk categories: low, low - moderate, moderate - high, very high. The Framingham risk category (scale) = FRS to estimate the risk of a CV event over the next 10 years. The FRS uses age, systolic blood pressure, high-density lipoprotein (HDL) cholesterol level, total cholesterol level, and smoking status to create a score that is converted into a 10-year CV disease risk % that correlates into a risk category: low, moderate, moderate - high risk, very high. For both scales, low is the best and very high is the worst outcome |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Years of Military Service - Compare FRS to CAC | within 10 days of CT scan | Compare FRS category to CAC risk category for those with 10-14, 15-19, 20-24 and 25+ years of military service. Calculate Fisher's Exact test statistic and associated p values to look at the relationship between those with 10-14, 15-19, 20-24 and 25+ years of military service and FRS & CAC risk category. The CAC risk category (scale) = CAC score (estimated degree of calcium in coronary arteries, a number) + percentage by age to establish risks of future CV events. There are 5 risk categories: low, low - moderate, moderate - high, very high. The Framingham risk category (scale) = FRS to estimate the risk of a CV event over the next 10 years. The FRS uses age, systolic blood pressure, high-density lipoprotein and total cholesterol levels, and smoking status to create a score that is converted into a 10-year CV disease risk % that correlates into a risk category: low, moderate, moderate - high risk, very high. For both scales, low is the best and very high is the worst outcome |
| Additional Cardiovascular Risk Factors - Compare FRS to CAC | within 10 days of CT scan | Compare FRS category to CAC risk category for those with 1 risk factor (RF), vs 2 RF, vs 3 RF, vs 4 RF, vs 5 CV risk factors. Calculate Fisher's Exact test statistic and associated p values to look at the relationship between those with 1 RF, vs 2 RF, vs 3 RF, vs 4 RF, vs 5 CV RF and the FRS & CAC risk category. The CAC risk category (scale) = CAC score (estimated degree of calcium in coronary arteries, a number) + percentage by age to establish risks of future CV events. There are 5 risk categories: low, low - moderate, moderate - high, very high. The Framingham risk category (scale) = FRS to estimate the risk of a CV event over the next 10 years. The FRS uses age, systolic blood pressure, high-density lipoprotein and total cholesterol levels, and smoking status to create a score that is converted into a 10-year CV disease risk % that correlates into a risk category: low, moderate, moderate - high risk, very high. For both scales, low is the best and very high is the worst outcome |
| Metabolic Syndrome - CAC | within 10 days of CT scan | Compare CAC risk category between two groups, those that meet criteria for metabolic syndrome and those that do not, to see if there is an association between the groups and CAC risk category. The number of participants in each risk category will be added. Then the total number for each group will be used to calculate the correlation using Fisher's Exact test and reported as a p value. The CAC risk category (scale) = CAC score (estimated degree of calcium in coronary arteries, a number) + percentage by age to establish risks of future CV events. There are 5 risk categories: low, low - moderate, moderate - high, high, very high. Low risk is the best outcome, and very high risk is the worst |
| Metabolic Syndrome - Compare FRS to CAC | within 10 days of CT scan | Compare FRS category and CAC risk category for those meeting and not meeting criteria for metabolic syndrome. Calculate Fisher's Exact test statistic and associated p values to look at the relationship between the presence/absence of metabolic syndrome and the FRS and CAC risk category. The CAC risk category (scale) = CAC score (estimated degree of calcium in coronary arteries, a number) + percentage by age to establish risks of future CV events. There are 5 risk categories: low, low - moderate, moderate - high, very high. The Framingham risk category (scale) = FRS to estimate the risk of a CV event over the next 10 years. The FRS uses age, systolic blood pressure, high-density lipoprotein (HDL) cholesterol level, total cholesterol level, and smoking status to create a score that is converted into a 10-year CV disease risk % that correlates into a risk category: low, moderate, moderate - high risk, very high. For both scales, low is the best and very high is the worst outcome |
| PT Failures - CAC | within 10 days of CT scan | Compare CAC risk category between two groups, those with and without a PT failures, to see if there is an association between the groups and CAC risk category. The number of participants in each risk category will be added. Then the total number for each group will be used to calculate the correlation using Fisher's Exact test and reported as a p value. The CAC risk category (scale) = CAC score (estimated degree of calcium in coronary arteries, a number) + percentage by age to establish risks of future CV events. There are 5 risk categories: low, low - moderate, moderate - high, very high. Low risk is the best outcome, and very high risk is the worst outcome |
| Years of Military Service - CAC | within 10 days of CT scan | Compare CAC risk category among groups, those with 10-14, 15-19, 20-24, and 25+ years of military service, to see if there is an association between overall years of military service and CAC risk category. The number of participants in each risk category will be added. Then the total number for each group will be used to calculate the correlation using Fisher's Exact test and reported as a p value. The CAC risk category (scale) = CAC score (estimated degree of calcium in coronary arteries, a number) + percentage by age to establish risks of future CV events. There are 5 risk categories: low, low - moderate, moderate - high, very high. Low risk is the best outcome, and very high risk is the worst outcome |
| Additional Risk Factors - CAC | within 10 days of CT scan | Compare CAC risk category among groups, those with 1 risk factor (RF) vs. 2 RF, vs 3 RF, vs 4 RF, vs 5 RF (as listed in the inclusion criteria), to see if there is an association between the groups and CAC risk category. The number of participants in each risk category will be added. Then the total number for each group will be used to calculate the correlation using Fisher's Exact test and reported as a p value. The CAC risk category (scale) = CAC score (estimated degree of calcium in coronary arteries, a number) + percentage by age to establish risks of future CV events. There are 5 risk categories: low, low - moderate, moderate - high, very high. Low risk is the best outcome, and very high risk is the worst outcome |
| Living in the Doors - CAC | within 10 days of CT scan | Compare CAC risk category between two groups, those who lived in the dorm for \> 5 years and \< 5 years, to see if there is an association between the groups and CAC risk category. The number of participants in each risk category will be added. Then the total number for each group will be used to calculate the correlation using Fisher's Exact test and reported as a p value. The CAC risk category (scale) = CAC score (estimated degree of calcium in coronary arteries, a number) + percentage by age to establish risks of future CV events. There are 5 risk categories: low, low - moderate, moderate - high, high, very high. Low risk is the best outcome, and very high risk is the worst outcome |
| Living in the Dorms - Compare FRS to CAC | within 10 days of CT scan | Compare FRS category to CAC risk category for those who lived in the dorms \> 5 years and \< 5 years. Calculate Fisher's Exact test statistic and associated p values to look at the relationship between those who lived in the dorms \> 5 years and \< 5 years and the FRS and CAC risk category. The CAC risk category (scale) = CAC score (estimated degree of calcium in coronary arteries, a number) + percentage by age to establish risks of future CV events. There are 5 risk categories: low, low - moderate, moderate - high, very high. The Framingham risk category (scale) = FRS to estimate the risk of a CV event over the next 10 years. The FRS uses age, systolic blood pressure, high-density lipoprotein (HDL) cholesterol level, total cholesterol level, and smoking status to create a score that is converted into a 10-year CV disease risk % that correlates into a risk category: low, moderate, moderate - high risk, very high. For both scales, low is the best and very high is the worst outcome |
| Physical Fitness (PT) Failures - Compare FRS to CAC | within 10 days of CT scan | Compare FRS category to CAC risk category for those with and without PT failures. Calculate Fischer's Exact test statistic and associated p values to look at the relationship between those with and without PT failures and the FRS and CAC risk category. The CAC risk category (scale) = CAC score (estimated degree of calcium in coronary arteries, a number) + percentage by age to establish risks of future CV events. There are 5 risk categories: low, low - moderate, moderate - high, very high. The Framingham risk category (scale) = FRS to estimate the risk of a CV event over the next 10 years. The FRS uses age, systolic blood pressure, high-density lipoprotein (HDL) cholesterol level, total cholesterol level, and smoking status to create a score that is converted into a 10-year CV disease risk % that correlates into a risk category: low, moderate, moderate - high risk, very high. For both scales, low is the best and very high is the worst outcome |
Countries
United States
Participant flow
Recruitment details
5 withdrawn
Participants by arm
| Arm | Count |
|---|---|
| Coronary Artery Calcium (CAC) / Framingham Risk Score (FRS) Coronary Artery Calcium (CAC) scores are reported as a numerical value and a percentage for age that is then regarded in terms of risk categories. The Framingham Risk Score (FRS) is a standard of care for estimating risk of a cardiovascular event over the next 10 years | 107 |
| Total | 107 |
Withdrawals & dropouts
| Period | Reason | FG000 |
|---|---|---|
| Overall Study | withdrawn | 5 |
Baseline characteristics
| Characteristic | Coronary Artery Calcium (CAC) / Framingham Risk Score (FRS) | — |
|---|---|---|
| Age, Continuous | 40.78505 years STANDARD_DEVIATION 5.037647 | — |
| More than one cardiovascular risk factor | 107 Participants | — |
| Race and Ethnicity Not Collected | — | — Participants |
| Sex: Female, Male Female | 3 Participants | — |
| Sex: Female, Male Male | 104 Participants | — |
Adverse events
| Event type | EG000 affected / at risk |
|---|---|
| deaths Total, all-cause mortality | 0 / 104 |
| other Total, other adverse events | 0 / 104 |
| serious Total, serious adverse events | 0 / 104 |
Outcome results
Primary
Compare FRS to the CAC - At Least One Additional Risk Factor
Compare FRS risk category to CAC risk category for enlisted subjects with at least 10 years of service and at least one additional CV risk factor to determine how well the results correlate with one another using the Spearman's Rank Correlation Coefficient. The CAC risk category (scale) = CAC score (estimated degree of calcium in coronary arteries, a number) + percentage by age to establish risks of future CV events. There are 5 risk categories: low, low - moderate, moderate - high, very high. The Framingham risk category (scale) = FRS to estimate the risk of a CV event over the next 10 years. The FRS uses age, systolic blood pressure, high-density lipoprotein (HDL) cholesterol level, total cholesterol level, and smoking status to create a score that is converted into a 10-year CV disease risk % that correlates into a risk category: low, moderate, moderate - high risk, very high. For both scales, low is the best and very high is the worst outcome
Time frame: within 10 days of CT scan
Population: The data is separated into two rows for each arm. Each row corresponds to a group. Participants were placed into one of the two groups based on certain criteria. Each group has a different number of participants analyzed. The total for both groups (rows) is equal to the overall number of participants analyzed
| Arm | Measure | Group | Value (COUNT_OF_PARTICIPANTS) |
|---|---|---|---|
| Coronary Artery Calcium (CAC) | Compare FRS to the CAC - At Least One Additional Risk Factor | at least 1 additional risk factor | 56 Participants |
| Coronary Artery Calcium (CAC) | Compare FRS to the CAC - At Least One Additional Risk Factor | no additional risk factors | 51 Participants |
| CAC Risk Category | Compare FRS to the CAC - At Least One Additional Risk Factor | at least 1 additional risk factor | 56 Participants |
| CAC Risk Category | Compare FRS to the CAC - At Least One Additional Risk Factor | no additional risk factors | 51 Participants |
Comparison: Compare risk categories (FRS and CAC)p-value: 0.79Spearman's Rank Correlation Coefficient
Primary
Prevalence of Atherosclerosis
Percent of active duty enlisted military members with 10 or more years of military service determined to have a prevalence of atherosclerosis based on CAC risk category. The CAC risk category (scale), is derived from the CAC score (i.e., an estimate of the degree of atherosclerosis present in each participant's coronary arteries, reported as a number), and percentage by age to establish risk of future CV events. There are 5 risk categories: Low risk = CAC of 0 and no cardiovascular (CV) risk factors, Low - Moderate risk = CAC of 0 with CV risk factors, Moderate - High risk: CAC 1-100 and percentile for age \<75%, High risk = CAC 100-399 or percentile for age \>75%, Very high risk = CAC \>100 and percentile for age \>90% or CAC \>400. Low risk is the best outcome, and very high risk is the worst.
Time frame: within 10 days of CT scan
| Arm | Measure | Value (COUNT_OF_PARTICIPANTS) |
|---|---|---|
| Coronary Artery Calcium (CAC) | Prevalence of Atherosclerosis | 16 Participants |
95% CI: [9.4, 22.9]
Primary
Rate of Reclassification
Percent/Number of subject that were reclassified from FRS to CAC risk category using CAC scores. The CAC risk category (scale) = CAC score (estimated degree of calcium in coronary arteries, a number) + percentage by age to establish risks of future CV events. There are 5 risk categories: low, low - moderate, moderate - high, very high. The Framingham risk category (scale) = FRS to estimate the risk of a CV event over the next 10 years. The FRS uses age, systolic blood pressure, high-density lipoprotein (HDL) cholesterol level, total cholesterol level, and smoking status to create a score that is converted into a 10-year CV disease risk % that correlates into a risk category: low, moderate, moderate - high risk, very high. For both scales, low is the best and very high is the worst outcome
Time frame: within 10 days of CT scan
| Arm | Measure | Category | Value (COUNT_OF_PARTICIPANTS) |
|---|---|---|---|
| Coronary Artery Calcium (CAC) | Rate of Reclassification | higher risk category | 99 Participants |
| Coronary Artery Calcium (CAC) | Rate of Reclassification | lower risk category | 5 Participants |
| Coronary Artery Calcium (CAC) | Rate of Reclassification | same risk category | 3 Participants |
Secondary
Additional Cardiovascular Risk Factors - Compare FRS to CAC
Compare FRS category to CAC risk category for those with 1 risk factor (RF), vs 2 RF, vs 3 RF, vs 4 RF, vs 5 CV risk factors. Calculate Fisher's Exact test statistic and associated p values to look at the relationship between those with 1 RF, vs 2 RF, vs 3 RF, vs 4 RF, vs 5 CV RF and the FRS & CAC risk category. The CAC risk category (scale) = CAC score (estimated degree of calcium in coronary arteries, a number) + percentage by age to establish risks of future CV events. There are 5 risk categories: low, low - moderate, moderate - high, very high. The Framingham risk category (scale) = FRS to estimate the risk of a CV event over the next 10 years. The FRS uses age, systolic blood pressure, high-density lipoprotein and total cholesterol levels, and smoking status to create a score that is converted into a 10-year CV disease risk % that correlates into a risk category: low, moderate, moderate - high risk, very high. For both scales, low is the best and very high is the worst outcome
Time frame: within 10 days of CT scan
Population: No data collected for this analysis. Due to the relatively small sample size with positive CAC scores, sub-analyses for patients with 2 or more risk factors were not performed. This may be an area for investigation if a larger study population were enrolled
Secondary
Additional Risk Factors - CAC
Compare CAC risk category among groups, those with 1 risk factor (RF) vs. 2 RF, vs 3 RF, vs 4 RF, vs 5 RF (as listed in the inclusion criteria), to see if there is an association between the groups and CAC risk category. The number of participants in each risk category will be added. Then the total number for each group will be used to calculate the correlation using Fisher's Exact test and reported as a p value. The CAC risk category (scale) = CAC score (estimated degree of calcium in coronary arteries, a number) + percentage by age to establish risks of future CV events. There are 5 risk categories: low, low - moderate, moderate - high, very high. Low risk is the best outcome, and very high risk is the worst outcome
Time frame: within 10 days of CT scan
Population: No data collected for this analysis. Due to the relatively small sample size with positive CAC scores, sub-analyses for patients with 2 or more risk factors were not performed. This may be an area for investigation if a larger study population were enrolled
Secondary
Living in the Doors - CAC
Compare CAC risk category between two groups, those who lived in the dorm for \> 5 years and \< 5 years, to see if there is an association between the groups and CAC risk category. The number of participants in each risk category will be added. Then the total number for each group will be used to calculate the correlation using Fisher's Exact test and reported as a p value. The CAC risk category (scale) = CAC score (estimated degree of calcium in coronary arteries, a number) + percentage by age to establish risks of future CV events. There are 5 risk categories: low, low - moderate, moderate - high, high, very high. Low risk is the best outcome, and very high risk is the worst outcome
Time frame: within 10 days of CT scan
Population: The data is separated into two rows. Each row corresponds to a group. Participants were placed into one of the two groups based on certain criteria. Each group has a different number of participants analyzed. The total for both groups (rows) is equal to the overall number of participants analyzed
| Arm | Measure | Group | Category | Value (COUNT_OF_PARTICIPANTS) |
|---|---|---|---|---|
| Coronary Artery Calcium (CAC) | Living in the Doors - CAC | > 5 years living in dorms | low risk | 0 Participants |
| Coronary Artery Calcium (CAC) | Living in the Doors - CAC | > 5 years living in dorms | low - moderate risk | 7 Participants |
| Coronary Artery Calcium (CAC) | Living in the Doors - CAC | > 5 years living in dorms | moderate - high risk | 1 Participants |
| Coronary Artery Calcium (CAC) | Living in the Doors - CAC | > 5 years living in dorms | high risk | 2 Participants |
| Coronary Artery Calcium (CAC) | Living in the Doors - CAC | > 5 years living in dorms | very high risk | 0 Participants |
| Coronary Artery Calcium (CAC) | Living in the Doors - CAC | < 5 years living in dorms | low risk | 0 Participants |
| Coronary Artery Calcium (CAC) | Living in the Doors - CAC | < 5 years living in dorms | low - moderate risk | 84 Participants |
| Coronary Artery Calcium (CAC) | Living in the Doors - CAC | < 5 years living in dorms | moderate - high risk | 7 Participants |
| Coronary Artery Calcium (CAC) | Living in the Doors - CAC | < 5 years living in dorms | high risk | 4 Participants |
| Coronary Artery Calcium (CAC) | Living in the Doors - CAC | < 5 years living in dorms | very high risk | 2 Participants |
Comparison: CAC risk category (low, low-mod, moderate - high, high, and very high)p-value: 0.13Fisher Exact
Secondary
Living in the Dorms - Compare FRS to CAC
Compare FRS category to CAC risk category for those who lived in the dorms \> 5 years and \< 5 years. Calculate Fisher's Exact test statistic and associated p values to look at the relationship between those who lived in the dorms \> 5 years and \< 5 years and the FRS and CAC risk category. The CAC risk category (scale) = CAC score (estimated degree of calcium in coronary arteries, a number) + percentage by age to establish risks of future CV events. There are 5 risk categories: low, low - moderate, moderate - high, very high. The Framingham risk category (scale) = FRS to estimate the risk of a CV event over the next 10 years. The FRS uses age, systolic blood pressure, high-density lipoprotein (HDL) cholesterol level, total cholesterol level, and smoking status to create a score that is converted into a 10-year CV disease risk % that correlates into a risk category: low, moderate, moderate - high risk, very high. For both scales, low is the best and very high is the worst outcome
Time frame: within 10 days of CT scan
Population: The data is separated into two rows for each arm. Each row corresponds to a group. Participants were placed into one of the two groups based on certain criteria. Each group has a different number of participants analyzed. The total for both groups (rows) is equal to the overall number of participants analyzed
| Arm | Measure | Group | Category | Value (COUNT_OF_PARTICIPANTS) |
|---|---|---|---|---|
| Coronary Artery Calcium (CAC) | Living in the Dorms - Compare FRS to CAC | > 5 years living in dorms | low risk | 9 Participants |
| Coronary Artery Calcium (CAC) | Living in the Dorms - Compare FRS to CAC | > 5 years living in dorms | low - moderate / moderate risk | 0 Participants |
| Coronary Artery Calcium (CAC) | Living in the Dorms - Compare FRS to CAC | > 5 years living in dorms | moderate - high risk | 1 Participants |
| Coronary Artery Calcium (CAC) | Living in the Dorms - Compare FRS to CAC | > 5 years living in dorms | high risk | 0 Participants |
| Coronary Artery Calcium (CAC) | Living in the Dorms - Compare FRS to CAC | > 5 years living in dorms | very high risk | 0 Participants |
| Coronary Artery Calcium (CAC) | Living in the Dorms - Compare FRS to CAC | < 5 years living in dorms | low risk | 90 Participants |
| Coronary Artery Calcium (CAC) | Living in the Dorms - Compare FRS to CAC | < 5 years living in dorms | low - moderate / moderate risk | 1 Participants |
| Coronary Artery Calcium (CAC) | Living in the Dorms - Compare FRS to CAC | < 5 years living in dorms | moderate - high risk | 6 Participants |
| Coronary Artery Calcium (CAC) | Living in the Dorms - Compare FRS to CAC | < 5 years living in dorms | high risk | 0 Participants |
| Coronary Artery Calcium (CAC) | Living in the Dorms - Compare FRS to CAC | < 5 years living in dorms | very high risk | 0 Participants |
| CAC Risk Category | Living in the Dorms - Compare FRS to CAC | < 5 years living in dorms | moderate - high risk | 7 Participants |
| CAC Risk Category | Living in the Dorms - Compare FRS to CAC | > 5 years living in dorms | low risk | 0 Participants |
| CAC Risk Category | Living in the Dorms - Compare FRS to CAC | < 5 years living in dorms | low risk | 0 Participants |
| CAC Risk Category | Living in the Dorms - Compare FRS to CAC | > 5 years living in dorms | low - moderate / moderate risk | 7 Participants |
| CAC Risk Category | Living in the Dorms - Compare FRS to CAC | < 5 years living in dorms | very high risk | 2 Participants |
| CAC Risk Category | Living in the Dorms - Compare FRS to CAC | > 5 years living in dorms | moderate - high risk | 1 Participants |
| CAC Risk Category | Living in the Dorms - Compare FRS to CAC | < 5 years living in dorms | low - moderate / moderate risk | 84 Participants |
| CAC Risk Category | Living in the Dorms - Compare FRS to CAC | > 5 years living in dorms | high risk | 2 Participants |
| CAC Risk Category | Living in the Dorms - Compare FRS to CAC | < 5 years living in dorms | high risk | 4 Participants |
| CAC Risk Category | Living in the Dorms - Compare FRS to CAC | > 5 years living in dorms | very high risk | 0 Participants |
Comparison: FRS risk categories (low, moderate, mod -high, high, and very high)p-value: 0.56Fisher Exact
Comparison: CAC risk category (low, low-mod, moderate - high, high, and very high)p-value: 0.13Fisher Exact
Secondary
Metabolic Syndrome - CAC
Compare CAC risk category between two groups, those that meet criteria for metabolic syndrome and those that do not, to see if there is an association between the groups and CAC risk category. The number of participants in each risk category will be added. Then the total number for each group will be used to calculate the correlation using Fisher's Exact test and reported as a p value. The CAC risk category (scale) = CAC score (estimated degree of calcium in coronary arteries, a number) + percentage by age to establish risks of future CV events. There are 5 risk categories: low, low - moderate, moderate - high, high, very high. Low risk is the best outcome, and very high risk is the worst
Time frame: within 10 days of CT scan
Population: The data is separated into two rows. Each row corresponds to a group. Participants were placed into one of the two groups based on certain criteria. Each group has a different number of participants analyzed. The total for both groups (rows) is equal to the overall number of participants analyzed
| Arm | Measure | Group | Category | Value (COUNT_OF_PARTICIPANTS) |
|---|---|---|---|---|
| Coronary Artery Calcium (CAC) | Metabolic Syndrome - CAC | metabolic syndrome | high risk | 1 Participants |
| Coronary Artery Calcium (CAC) | Metabolic Syndrome - CAC | metabolic syndrome | very high risk | 0 Participants |
| Coronary Artery Calcium (CAC) | Metabolic Syndrome - CAC | metabolic syndrome | low risk | 0 Participants |
| Coronary Artery Calcium (CAC) | Metabolic Syndrome - CAC | metabolic syndrome | low - moderate risk | 18 Participants |
| Coronary Artery Calcium (CAC) | Metabolic Syndrome - CAC | metabolic syndrome | moderate - high risk | 4 Participants |
| Coronary Artery Calcium (CAC) | Metabolic Syndrome - CAC | no metabolic syndrome | low risk | 0 Participants |
| Coronary Artery Calcium (CAC) | Metabolic Syndrome - CAC | no metabolic syndrome | low - moderate risk | 73 Participants |
| Coronary Artery Calcium (CAC) | Metabolic Syndrome - CAC | no metabolic syndrome | moderate - high risk | 4 Participants |
| Coronary Artery Calcium (CAC) | Metabolic Syndrome - CAC | no metabolic syndrome | high risk | 5 Participants |
| Coronary Artery Calcium (CAC) | Metabolic Syndrome - CAC | no metabolic syndrome | very high risk | 2 Participants |
Comparison: CAC risk category (low, low-mod, mod-high, high, very high)p-value: 0.21Fisher Exact
Secondary
Metabolic Syndrome - Compare FRS to CAC
Compare FRS category and CAC risk category for those meeting and not meeting criteria for metabolic syndrome. Calculate Fisher's Exact test statistic and associated p values to look at the relationship between the presence/absence of metabolic syndrome and the FRS and CAC risk category. The CAC risk category (scale) = CAC score (estimated degree of calcium in coronary arteries, a number) + percentage by age to establish risks of future CV events. There are 5 risk categories: low, low - moderate, moderate - high, very high. The Framingham risk category (scale) = FRS to estimate the risk of a CV event over the next 10 years. The FRS uses age, systolic blood pressure, high-density lipoprotein (HDL) cholesterol level, total cholesterol level, and smoking status to create a score that is converted into a 10-year CV disease risk % that correlates into a risk category: low, moderate, moderate - high risk, very high. For both scales, low is the best and very high is the worst outcome
Time frame: within 10 days of CT scan
Population: The data is separated into two rows for each arm. Each row corresponds to a group. Participants were placed into one of the two groups based on certain criteria. Each group has a different number of participants analyzed. The total for both groups (rows) is equal to the overall number of participants analyzed
| Arm | Measure | Group | Category | Value (COUNT_OF_PARTICIPANTS) |
|---|---|---|---|---|
| Coronary Artery Calcium (CAC) | Metabolic Syndrome - Compare FRS to CAC | metabolic syndrome | very high risk | 0 Participants |
| Coronary Artery Calcium (CAC) | Metabolic Syndrome - Compare FRS to CAC | metabolic syndrome | low risk | 19 Participants |
| Coronary Artery Calcium (CAC) | Metabolic Syndrome - Compare FRS to CAC | metabolic syndrome | low - moderate / moderate risk | 1 Participants |
| Coronary Artery Calcium (CAC) | Metabolic Syndrome - Compare FRS to CAC | metabolic syndrome | moderate - high risk | 3 Participants |
| Coronary Artery Calcium (CAC) | Metabolic Syndrome - Compare FRS to CAC | metabolic syndrome | high risk | 0 Participants |
| Coronary Artery Calcium (CAC) | Metabolic Syndrome - Compare FRS to CAC | no metabolic syndrome | low risk | 80 Participants |
| Coronary Artery Calcium (CAC) | Metabolic Syndrome - Compare FRS to CAC | no metabolic syndrome | low - moderate / moderate risk | 0 Participants |
| Coronary Artery Calcium (CAC) | Metabolic Syndrome - Compare FRS to CAC | no metabolic syndrome | moderate - high risk | 4 Participants |
| Coronary Artery Calcium (CAC) | Metabolic Syndrome - Compare FRS to CAC | no metabolic syndrome | high risk | 0 Participants |
| Coronary Artery Calcium (CAC) | Metabolic Syndrome - Compare FRS to CAC | no metabolic syndrome | very high risk | 0 Participants |
| CAC Risk Category | Metabolic Syndrome - Compare FRS to CAC | no metabolic syndrome | moderate - high risk | 4 Participants |
| CAC Risk Category | Metabolic Syndrome - Compare FRS to CAC | no metabolic syndrome | low risk | 0 Participants |
| CAC Risk Category | Metabolic Syndrome - Compare FRS to CAC | metabolic syndrome | low risk | 0 Participants |
| CAC Risk Category | Metabolic Syndrome - Compare FRS to CAC | no metabolic syndrome | very high risk | 2 Participants |
| CAC Risk Category | Metabolic Syndrome - Compare FRS to CAC | metabolic syndrome | low - moderate / moderate risk | 18 Participants |
| CAC Risk Category | Metabolic Syndrome - Compare FRS to CAC | no metabolic syndrome | low - moderate / moderate risk | 73 Participants |
| CAC Risk Category | Metabolic Syndrome - Compare FRS to CAC | metabolic syndrome | moderate - high risk | 4 Participants |
| CAC Risk Category | Metabolic Syndrome - Compare FRS to CAC | no metabolic syndrome | high risk | 5 Participants |
| CAC Risk Category | Metabolic Syndrome - Compare FRS to CAC | metabolic syndrome | high risk | 1 Participants |
| CAC Risk Category | Metabolic Syndrome - Compare FRS to CAC | metabolic syndrome | very high risk | 0 Participants |
Comparison: FRS risk category (low, mod, mod-high, high, very high risk)p-value: 0.063Fisher Exact
Comparison: CAC risk category (low, low-mod, mod-high, high, very high)p-value: 0.21Fisher Exact
Secondary
Physical Fitness (PT) Failures - Compare FRS to CAC
Compare FRS category to CAC risk category for those with and without PT failures. Calculate Fischer's Exact test statistic and associated p values to look at the relationship between those with and without PT failures and the FRS and CAC risk category. The CAC risk category (scale) = CAC score (estimated degree of calcium in coronary arteries, a number) + percentage by age to establish risks of future CV events. There are 5 risk categories: low, low - moderate, moderate - high, very high. The Framingham risk category (scale) = FRS to estimate the risk of a CV event over the next 10 years. The FRS uses age, systolic blood pressure, high-density lipoprotein (HDL) cholesterol level, total cholesterol level, and smoking status to create a score that is converted into a 10-year CV disease risk % that correlates into a risk category: low, moderate, moderate - high risk, very high. For both scales, low is the best and very high is the worst outcome
Time frame: within 10 days of CT scan
Population: 1 subject had no data. Data are separated into 2 rows (groups). Participants were placed into 1 of 2 groups based on certain criteria. Each group has a different number of participants. The total for both groups (rows) is equal to the overall number of participants analyzed
| Arm | Measure | Group | Category | Value (COUNT_OF_PARTICIPANTS) |
|---|---|---|---|---|
| Coronary Artery Calcium (CAC) | Physical Fitness (PT) Failures - Compare FRS to CAC | with PT failure | low risk | 48 Participants |
| Coronary Artery Calcium (CAC) | Physical Fitness (PT) Failures - Compare FRS to CAC | with PT failure | low - moderate / moderate risk | 0 Participants |
| Coronary Artery Calcium (CAC) | Physical Fitness (PT) Failures - Compare FRS to CAC | with PT failure | moderate - high risk | 5 Participants |
| Coronary Artery Calcium (CAC) | Physical Fitness (PT) Failures - Compare FRS to CAC | with PT failure | high risk | 0 Participants |
| Coronary Artery Calcium (CAC) | Physical Fitness (PT) Failures - Compare FRS to CAC | with PT failure | very high risk | 0 Participants |
| Coronary Artery Calcium (CAC) | Physical Fitness (PT) Failures - Compare FRS to CAC | without PT failure | low risk | 50 Participants |
| Coronary Artery Calcium (CAC) | Physical Fitness (PT) Failures - Compare FRS to CAC | without PT failure | low - moderate / moderate risk | 1 Participants |
| Coronary Artery Calcium (CAC) | Physical Fitness (PT) Failures - Compare FRS to CAC | without PT failure | moderate - high risk | 2 Participants |
| Coronary Artery Calcium (CAC) | Physical Fitness (PT) Failures - Compare FRS to CAC | without PT failure | high risk | 0 Participants |
| Coronary Artery Calcium (CAC) | Physical Fitness (PT) Failures - Compare FRS to CAC | without PT failure | very high risk | 0 Participants |
| CAC Risk Category | Physical Fitness (PT) Failures - Compare FRS to CAC | without PT failure | moderate - high risk | 5 Participants |
| CAC Risk Category | Physical Fitness (PT) Failures - Compare FRS to CAC | with PT failure | low risk | 0 Participants |
| CAC Risk Category | Physical Fitness (PT) Failures - Compare FRS to CAC | without PT failure | low risk | 0 Participants |
| CAC Risk Category | Physical Fitness (PT) Failures - Compare FRS to CAC | with PT failure | low - moderate / moderate risk | 46 Participants |
| CAC Risk Category | Physical Fitness (PT) Failures - Compare FRS to CAC | without PT failure | very high risk | 0 Participants |
| CAC Risk Category | Physical Fitness (PT) Failures - Compare FRS to CAC | with PT failure | moderate - high risk | 3 Participants |
| CAC Risk Category | Physical Fitness (PT) Failures - Compare FRS to CAC | without PT failure | low - moderate / moderate risk | 44 Participants |
| CAC Risk Category | Physical Fitness (PT) Failures - Compare FRS to CAC | with PT failure | high risk | 2 Participants |
| CAC Risk Category | Physical Fitness (PT) Failures - Compare FRS to CAC | without PT failure | high risk | 4 Participants |
| CAC Risk Category | Physical Fitness (PT) Failures - Compare FRS to CAC | with PT failure | very high risk | 2 Participants |
Comparison: FRS risk categories (low, moderate, moderate-high, high, and very high)p-value: 0.44Fisher Exact
Comparison: CAC risk categories (low, low-moderate, mod -high, high, and very high)p-value: 0.49Fisher Exact
Secondary
PT Failures - CAC
Compare CAC risk category between two groups, those with and without a PT failures, to see if there is an association between the groups and CAC risk category. The number of participants in each risk category will be added. Then the total number for each group will be used to calculate the correlation using Fisher's Exact test and reported as a p value. The CAC risk category (scale) = CAC score (estimated degree of calcium in coronary arteries, a number) + percentage by age to establish risks of future CV events. There are 5 risk categories: low, low - moderate, moderate - high, very high. Low risk is the best outcome, and very high risk is the worst outcome
Time frame: within 10 days of CT scan
Population: 1 subject had no data. Data are separated into 2 rows (groups). Participants were placed into 1 of 2 groups based on certain criteria. Each group has a different number of participants. The total for both groups (rows) is equal to the overall number of participants analyzed
| Arm | Measure | Group | Category | Value (COUNT_OF_PARTICIPANTS) |
|---|---|---|---|---|
| Coronary Artery Calcium (CAC) | PT Failures - CAC | with PT failures | low risk | 0 Participants |
| Coronary Artery Calcium (CAC) | PT Failures - CAC | with PT failures | low - moderate risk | 46 Participants |
| Coronary Artery Calcium (CAC) | PT Failures - CAC | with PT failures | moderate - high risk | 3 Participants |
| Coronary Artery Calcium (CAC) | PT Failures - CAC | with PT failures | high risk | 2 Participants |
| Coronary Artery Calcium (CAC) | PT Failures - CAC | with PT failures | very high risk | 2 Participants |
| Coronary Artery Calcium (CAC) | PT Failures - CAC | without PT failures | low risk | 0 Participants |
| Coronary Artery Calcium (CAC) | PT Failures - CAC | without PT failures | low - moderate risk | 44 Participants |
| Coronary Artery Calcium (CAC) | PT Failures - CAC | without PT failures | moderate - high risk | 5 Participants |
| Coronary Artery Calcium (CAC) | PT Failures - CAC | without PT failures | high risk | 4 Participants |
| Coronary Artery Calcium (CAC) | PT Failures - CAC | without PT failures | very high risk | 0 Participants |
Comparison: CAC risk categories (low, low-moderate, mod -high, high, and very high)p-value: 0.49Fisher Exact
Secondary
Years of Military Service - CAC
Compare CAC risk category among groups, those with 10-14, 15-19, 20-24, and 25+ years of military service, to see if there is an association between overall years of military service and CAC risk category. The number of participants in each risk category will be added. Then the total number for each group will be used to calculate the correlation using Fisher's Exact test and reported as a p value. The CAC risk category (scale) = CAC score (estimated degree of calcium in coronary arteries, a number) + percentage by age to establish risks of future CV events. There are 5 risk categories: low, low - moderate, moderate - high, very high. Low risk is the best outcome, and very high risk is the worst outcome
Time frame: within 10 days of CT scan
Population: The data is separated into 4 rows. Each row corresponds to a group. Participants were placed into one of the 4 groups based on certain criteria. Each group has a different number of participants analyzed. The total for all groups (rows) is equal to the overall number of participants analyzed
| Arm | Measure | Group | Category | Value (COUNT_OF_PARTICIPANTS) |
|---|---|---|---|---|
| Coronary Artery Calcium (CAC) | Years of Military Service - CAC | 10-14 years of military service | low risk | 0 Participants |
| Coronary Artery Calcium (CAC) | Years of Military Service - CAC | 10-14 years of military service | low - moderate risk | 7 Participants |
| Coronary Artery Calcium (CAC) | Years of Military Service - CAC | 10-14 years of military service | moderate - high risk | 0 Participants |
| Coronary Artery Calcium (CAC) | Years of Military Service - CAC | 10-14 years of military service | high risk | 0 Participants |
| Coronary Artery Calcium (CAC) | Years of Military Service - CAC | 10-14 years of military service | very high risk | 0 Participants |
| Coronary Artery Calcium (CAC) | Years of Military Service - CAC | 15-19 years of military service | low risk | 0 Participants |
| Coronary Artery Calcium (CAC) | Years of Military Service - CAC | 15-19 years of military service | low - moderate risk | 40 Participants |
| Coronary Artery Calcium (CAC) | Years of Military Service - CAC | 15-19 years of military service | moderate - high risk | 1 Participants |
| Coronary Artery Calcium (CAC) | Years of Military Service - CAC | 15-19 years of military service | high risk | 3 Participants |
| Coronary Artery Calcium (CAC) | Years of Military Service - CAC | 15-19 years of military service | very high risk | 0 Participants |
| Coronary Artery Calcium (CAC) | Years of Military Service - CAC | 20-24 years of military service | low risk | 0 Participants |
| Coronary Artery Calcium (CAC) | Years of Military Service - CAC | 20-24 years of military service | low - moderate risk | 35 Participants |
| Coronary Artery Calcium (CAC) | Years of Military Service - CAC | 20-24 years of military service | moderate - high risk | 1 Participants |
| Coronary Artery Calcium (CAC) | Years of Military Service - CAC | 20-24 years of military service | high risk | 3 Participants |
| Coronary Artery Calcium (CAC) | Years of Military Service - CAC | 20-24 years of military service | very high risk | 1 Participants |
| Coronary Artery Calcium (CAC) | Years of Military Service - CAC | 25 or more years of military service | low risk | 0 Participants |
| Coronary Artery Calcium (CAC) | Years of Military Service - CAC | 25 or more years of military service | low - moderate risk | 9 Participants |
| Coronary Artery Calcium (CAC) | Years of Military Service - CAC | 25 or more years of military service | moderate - high risk | 6 Participants |
| Coronary Artery Calcium (CAC) | Years of Military Service - CAC | 25 or more years of military service | high risk | 0 Participants |
| Coronary Artery Calcium (CAC) | Years of Military Service - CAC | 25 or more years of military service | very high risk | 1 Participants |
Comparison: CAC risk category (low, low-mod, mod-high, high, very high risk)p-value: 0.003Fisher Exact
Secondary
Years of Military Service - Compare FRS to CAC
Compare FRS category to CAC risk category for those with 10-14, 15-19, 20-24 and 25+ years of military service. Calculate Fisher's Exact test statistic and associated p values to look at the relationship between those with 10-14, 15-19, 20-24 and 25+ years of military service and FRS & CAC risk category. The CAC risk category (scale) = CAC score (estimated degree of calcium in coronary arteries, a number) + percentage by age to establish risks of future CV events. There are 5 risk categories: low, low - moderate, moderate - high, very high. The Framingham risk category (scale) = FRS to estimate the risk of a CV event over the next 10 years. The FRS uses age, systolic blood pressure, high-density lipoprotein and total cholesterol levels, and smoking status to create a score that is converted into a 10-year CV disease risk % that correlates into a risk category: low, moderate, moderate - high risk, very high. For both scales, low is the best and very high is the worst outcome
Time frame: within 10 days of CT scan
Population: Unable to perform statistical test for 10-14 years of service due to small number of subjects (7). Data are separated into 4 rows (groups). Participants were placed into 1 of 4 groups based on certain criteria. Each group has a different number of participants. The total for all groups (rows) is equal to the overall number of participants analyzed
| Arm | Measure | Group | Category | Value (COUNT_OF_PARTICIPANTS) |
|---|---|---|---|---|
| Coronary Artery Calcium (CAC) | Years of Military Service - Compare FRS to CAC | 15-19 years of military service | very high risk | 0 Participants |
| Coronary Artery Calcium (CAC) | Years of Military Service - Compare FRS to CAC | 20-24 years of military service | high risk | 0 Participants |
| Coronary Artery Calcium (CAC) | Years of Military Service - Compare FRS to CAC | 15-19 years of military service | low - moderate / moderate risk | 0 Participants |
| Coronary Artery Calcium (CAC) | Years of Military Service - Compare FRS to CAC | 20-24 years of military service | very high risk | 0 Participants |
| Coronary Artery Calcium (CAC) | Years of Military Service - Compare FRS to CAC | 20-24 years of military service | low risk | 39 Participants |
| Coronary Artery Calcium (CAC) | Years of Military Service - Compare FRS to CAC | 25 or more years of military service | low risk | 14 Participants |
| Coronary Artery Calcium (CAC) | Years of Military Service - Compare FRS to CAC | 15-19 years of military service | high risk | 0 Participants |
| Coronary Artery Calcium (CAC) | Years of Military Service - Compare FRS to CAC | 25 or more years of military service | low - moderate / moderate risk | 0 Participants |
| Coronary Artery Calcium (CAC) | Years of Military Service - Compare FRS to CAC | 20-24 years of military service | low - moderate / moderate risk | 1 Participants |
| Coronary Artery Calcium (CAC) | Years of Military Service - Compare FRS to CAC | 25 or more years of military service | moderate - high | 2 Participants |
| Coronary Artery Calcium (CAC) | Years of Military Service - Compare FRS to CAC | 15-19 years of military service | moderate - high | 4 Participants |
| Coronary Artery Calcium (CAC) | Years of Military Service - Compare FRS to CAC | 25 or more years of military service | high risk | 0 Participants |
| Coronary Artery Calcium (CAC) | Years of Military Service - Compare FRS to CAC | 20-24 years of military service | moderate - high | 0 Participants |
| Coronary Artery Calcium (CAC) | Years of Military Service - Compare FRS to CAC | 25 or more years of military service | very high risk | 0 Participants |
| Coronary Artery Calcium (CAC) | Years of Military Service - Compare FRS to CAC | 15-19 years of military service | low risk | 40 Participants |
| CAC Risk Category | Years of Military Service - Compare FRS to CAC | 25 or more years of military service | very high risk | 1 Participants |
| CAC Risk Category | Years of Military Service - Compare FRS to CAC | 15-19 years of military service | low risk | 0 Participants |
| CAC Risk Category | Years of Military Service - Compare FRS to CAC | 15-19 years of military service | low - moderate / moderate risk | 40 Participants |
| CAC Risk Category | Years of Military Service - Compare FRS to CAC | 15-19 years of military service | moderate - high | 1 Participants |
| CAC Risk Category | Years of Military Service - Compare FRS to CAC | 15-19 years of military service | high risk | 3 Participants |
| CAC Risk Category | Years of Military Service - Compare FRS to CAC | 15-19 years of military service | very high risk | 0 Participants |
| CAC Risk Category | Years of Military Service - Compare FRS to CAC | 20-24 years of military service | low risk | 0 Participants |
| CAC Risk Category | Years of Military Service - Compare FRS to CAC | 20-24 years of military service | low - moderate / moderate risk | 35 Participants |
| CAC Risk Category | Years of Military Service - Compare FRS to CAC | 20-24 years of military service | moderate - high | 1 Participants |
| CAC Risk Category | Years of Military Service - Compare FRS to CAC | 20-24 years of military service | high risk | 3 Participants |
| CAC Risk Category | Years of Military Service - Compare FRS to CAC | 20-24 years of military service | very high risk | 1 Participants |
| CAC Risk Category | Years of Military Service - Compare FRS to CAC | 25 or more years of military service | low risk | 0 Participants |
| CAC Risk Category | Years of Military Service - Compare FRS to CAC | 25 or more years of military service | low - moderate / moderate risk | 9 Participants |
| CAC Risk Category | Years of Military Service - Compare FRS to CAC | 25 or more years of military service | moderate - high | 6 Participants |
| CAC Risk Category | Years of Military Service - Compare FRS to CAC | 25 or more years of military service | high risk | 0 Participants |
Comparison: FRS risk categories (low, moderate, moderate -high, high, and very high)p-value: 0.11Fisher Exact
Comparison: CAC risk category (low, low-mod, mod-high, high, very high risk)p-value: 0.003Fisher Exact