Taurolidine Lock in Long Term Parenteral Nutrition

The Value of Taurolidine Lock in Long Term Parenteral Nutrition

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02009189

Enrollment

Registered

2013-12-11

Start date

2012-11-30

Completion date

2013-12-31

Last updated

2013-12-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Central Venous Catheter, Home Parenteral Nutrition

Keywords

home parenteral nutrition, central venous catheter

Brief summary

Taurolidine alone or in combination with citrate have been proposed for locking the catheter to reduce the number of catheter infections. As there is not enough evidence to give recommendations in this regard, the study tested the hipothesis that taurolidine improves the outcome of long term paretneral nutrition.

Interventions

DRUG2% Taurolidine Lock

Catheter lock with 2% Taurolidine

DRUG1.35% Taurolidine

Catheter lock with 1.35% Taurolidine + citrate

Study design

Allocation

RANDOMIZED

Intervention model

FACTORIAL

Primary purpose

PREVENTION

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* home parenteral nutrition for at least months before enrollment * presence of central venous cathter

Exclusion criteria

* home nutrition \< 12 months * catheter in peripheral vein

Design outcomes

Primary

Measure	Time frame	Description
Number of CVC infections	12 months	Number of central venous catheter infections

Countries

Poland

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026