Azoospermia
Conditions
Keywords
Stem cell, infertility, Azoospermia
Brief summary
Azoospermia due to low sperm production (non-obstructive azoospermia) affects approximately 1% of the male population and 10% of men who seek fertility evaluation. Testis biopsy reveals that these men have Sertoli cell-only pattern, maturation arrest, or hypospermatogenesis. Until recently, it was assumed that men with non-obstructive azoospermia were untreatable. Indeed, these patients were often referred to as being sterile or having testicular failure. We start to use stem cell in treatment of such patients by injecting the stem cell at the testis and the testicular artery in one group and at the testis only in other group
Interventions
PROCEDUREBone marrow stem cell injection
Injection should be in testis and testicular artery
Sponsors
Man Clinic for Andrology, Male Infertility and Sexual Dysfunction
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
SINGLE (Investigator)
Eligibility
Sex/Gender
MALE
Healthy volunteers
No
Inclusion criteria
\- Azoospermia
Exclusion criteria
\- Absent or surgical removed testes
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Semen Analysis | Three to six months | After stem cell injection by three to six months we evaluate the outcome by semen analysis |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Inhibin B Hormone | Three to six months | If semen analysis still azoo we do Inhibin B Hormone |
Countries
Egypt
Contacts
Primary ContactKhaled A Gadalla, MD
Outcome results
None listed