Lung Cancer(Primary, Metastatic), Benign Lung Mass Requiring Operation
Conditions
Keywords
Systemic lidocaine, postoperative pain, Video-assisted thoracic surgery, VATS
Brief summary
Systemic lidocaine infusion may improve the patients' chronic post surgical pain after video-assisted thoracic surgery
Interventions
In group L, intravenous lidocaine infusion(0.1mg/kg) for 10minutes after induction of anesthesia. After 10 minutes, lidocaine infusion continued at rate of 3mg/kg/hr during operation, and discontinued before move the patients to PACU.
In group C, the patients receive same volume of normal saline
Sponsors
Yonsei University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
20 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* Age between 20 and 65 years * ASA class 1 and 2 * Patients who are scheduled for video-assisted thoracic surgery
Exclusion criteria
* Allergy to local anesthetics or contraindication to use of lidocaine * Pregnancy * Severe cardiovascular disease * Renal failure * Liver failure * Neurologic and psychologic disease * Chronic treatment with analgesics or chronic pain patients * Previous history of thoracic surgery (open or video-assisted) * Patients' refusal
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Assessing pain score after operation | 2 months after operation | Assessing pain score by Short-form McGill pain questionnaire at 2 months after operation |
Countries
South Korea
Outcome results
None listed