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Beneficial Effects of Microsurgical Varicocelectomy on Semen Parameters for Causes Other Than Infertility

Beneficial Effects of Microsurgical Varicocelectomy on Semen Parameters in Patients Who Underwent Surgery for Causes Other Than Infertility

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT02006316
Enrollment
121
Registered
2013-12-10
Start date
2000-01-31
Completion date
2010-03-31
Last updated
2014-05-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Varicocele

Brief summary

The purpose of this study is to evaluate whether clinical varicoceles are associated with abnormal semen parameters and whether varicocelectomy could improve the semen parameter in patients unrelated with infertility.

Detailed description

While most studies are continued to validate the observations of significant improvements in sperm density and motility after varicocele ligation in infertile patients, there have been few studies to investigate the effects of varicocelectomy on semen parameters in adult men unrelated with infertility. The purpose of this study was to determine whether varicocelectomy could improve the semen parameter of these patients as well as whether clinical varicoceles are associated with abnormal semen parameters in patients unrelated with infertility.

Interventions

PROCEDUREMicrosurgical subinguinal varicocelectomy

Sponsors

Seoul National University Hospital
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
MALE
Age
20 Years to 45 Years
Healthy volunteers
No

Inclusion criteria

* men with clinical varicoceles underwent microsurgical varicocelectomy due to causes other than infertility such as testicular pain, discomfort or scrotal mass

Exclusion criteria

* adolescents * men with proven fertility or azoospermia * men with preoperative normal sperm analysis * available data to compare between preoperative and postoperative semen analyses

Design outcomes

Primary

MeasureTime frameDescription
Sperm concentration, motility, and morphologyat postoperative 4monthsTo observe the change of sperm concentration, motility, and morphology pre and postoperatively in the patients of inclusion criteria

Secondary

MeasureTime frameDescription
whether semen analysis should be done in men with clinical varicocele regardless of the chief complaintat postoperative 4monthsthis result would show the need of performing semen analysis even in the patients with clinical varicocels due to causes other than infertility

Countries

South Korea

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026