Insulin Sensitivity, Weight
Conditions
Keywords
Insulin sensitivity, Lipid profile, Body composition, Weight
Brief summary
Intervention studying the effect of a low-carbohydrate/high-fat (LCHF) diet as well as on bout of exercise in combination with either a normal diet or a LCHF diet, in relation to glucose metabolism, insulin sensitivity, lipid profile and body composition.
Interventions
OTHERLCHF diet and a bout of exercise
Low-carbohydrate/high-fat diet; effect on insulin sensitivity, lipid profile, weight and body composition. Participants ingested LCHF diet for three weeks before undergoing an oral glucose tolerance test. The same afternoon the participated in an one hour indoor bicycle training at 75% at HFpeak. The following morning they underwent a new oral glucose tolerance test. Body composition and weight were measured before and after the intervention. Oral glucose tolerance test was also performed before the intervention for baseline. Blood samples were collected before and after the intervention for lipid profile analyses.
Sponsors
Norwegian School of Sport Sciences
Atlantis Medical University College
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 30 Years
Healthy volunteers
Yes
Inclusion criteria
* Females * Normal weight * BMI between 18.5 and 25 * Moderately trained
Exclusion criteria
* Smokers/tobacco users * pregnancy * familial cardio-vascular-disease * diabetes or reduced glucose tolerance * under- or overweight (BMI under 18.5 or over 25) * top athletes
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Area under the curve glucose (0, 15, 30, 45, 60, 90 and 120 min) | -1 week, 3 weeks | performed by oral glucose tolerance test, 75 g glucose, 300 ml water |
Countries
Norway
Outcome results
None listed