High Risk Cardiovascular Disease Patients
Conditions
Keywords
cardiovascular disease, metabolic disease, high risk, prospective cohort
Brief summary
Set the prospective cohort (CMERC-HI) to study the known and novel etiologies and related factors for predicting clinical outcomes in Korean patients with high risk cardiovascular disease.
Interventions
None listed
Sponsors
Yonsei University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
20 Years to 80 Years
Healthy volunteers
Yes
Inclusion criteria
* high risk hypertension patients a. eGFR \> 60 with one of target organ damages b. eGFR \<= 60 * diabetes mellitus with microalbumin ration (AC ratio \>= 30mg/g) * anuric ESRD patients on dialysis * the relatives of acute myocardial infarction patients under 55 years old (men)/ 65 years old (women) * atherosclerotic cardiovascular disease (abdominal aorta diameter ≥3 cm or ankle-brachial index \<0.9, or carotid plaque or carotid intima-media thickness ≥0.9 mm, or asymptomatic old cerebrovascular accident, or \>30% stenosis in at least one major coronary artery) * rheumatoid arthritis patients aged \> 40 years on MTX and steroid therapy * atrial fibrillation patients with CHADS-VASc Score ≥ 1 * kidney transplant recipient at \> 3 months after transplantation
Exclusion criteria
* acute myocardial infarction, acute coronary syndrome patients, symptomatic coronary artery disease or history of these diseases * symptomatic peripheral artery disease, heart failure and history of these diseases * desired life time under 6 months due to non-cardiovascular disease (e.g. cancer, sepsis) * women with pregnancy or on nursing * history of contrast allergy and related side effects * within the first three months after transplantation * acute renal allograft rejection
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Prognosis of high risk cardiovascular disease | 10 year after recruting | all-cause mortality, cardiovascular mortality, non-cardiovascular mortality new onset of acute myocardial infarction, acute coronary syndrome, heart failure, stroke, peripheral artery disease, hospitalization for revascularization and these disease |
Countries
South Korea
Contacts
Primary ContactSungha Park, MD
Outcome results
None listed