Botulinum Toxin Injection to Prevent VT Storm

Endomyocardial Botulinum Toxin Injection Can Decrease the Number of Episodes of VT Storm: Pilot Study

Status

UNKNOWN

Phases

Phase 1

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02003027

Enrollment

Registered

2013-12-06

Start date

2013-06-30

Completion date

2016-01-31

Last updated

2015-09-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

VT Storm

Brief summary

The aim of this prospective non-randomized study was to assess the efficacy and safety of endomyocardial botulinum toxin injection in left ventricle for preventing episodes of VT Storm.

Interventions

DRUGBT injection

Study design

Allocation

NON_RANDOMIZED

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 70 Years

Healthy volunteers

Inclusion criteria

* 3 or more episodes of ventricular tachycardia within 24 hours

Exclusion criteria

* Failure to provide informed consent. * Non-cardiac illness with a life expectancy of less than 3 year * Non-cardiac illness imposing substantial operative mortality * Current participation in another clinical trial in which a patient is taking an investigational drug or receiving an investigational medical device

Design outcomes

Primary

Measure	Time frame
number of episodes of VT Storm	1 year

Secondary

Measure	Time frame
serious adverse events	1 year

Countries

Russia

Contacts

Primary ContactEvgeny Pokushalov, MD, PhD

e.pokushalov@gmail.com+79139254858

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026