Diabetes Mellitus
Conditions
Keywords
pancreatic cancer, new-onset diabetic, diabetes
Brief summary
The purpose of this study is to create a prospective cohort of subjects with increased probability of being diagnosed with pancreatic cancer and then screen this cohort for pancreatic cancer
Detailed description
Compared to the general population, subjects \>50 years of age with new-onset diabetes (DM) are 8-times more likely to have pancreatic cancer (PaC). The likelihood of PaC in new-onset DM is further increased in those who have weight loss or elevated CA19-9. In this study patients with newly diagnosed diabetes will be prospectively identified. Those with weight loss and/or elevated pancreatic cancer marker (CA 19-9) will undergo pancreatic imaging. All subjects will be followed up to 24 months. If successful in identifying surgically removable PaC, this study will fundamentally change our practice and will be a major breakthrough in PaC treatment and research.
Interventions
OTHERmedical chart review
baseline, quarterly follow-up for 24 months
OTHERsurvey administration
baseline
OTHERSpecimen collection
baseline
Sponsors
Mayo Clinic
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
50 Years to 85 Years
Healthy volunteers
No
Inclusion criteria
Patient Characteristics: --Suspected or definite new-onset diabetes based on recent blood sugar and hemoglobin A1c values * No acute illness or steroid therapy * No prior pancreas surgery
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| To create a prospective cohort of subjects with increased probability of being diagnosed with pancreatic cancer and identify pancreatic cancer in this cohort. | Follow subjects for 2 years. | We will prospectively identify patients with newly diagnosed diabetes and perform pancreatic imaging to identify pancreatic cancer |
Countries
United States
Outcome results
None listed