Effect of Chlorhexidine Gel on Bacterial Count During Fixed Orthodontic Treatment

Effect of Chlorhexidine Gel on Bacterial Count and Orthodontic Brackets During Fixed Orthodontic Treatment; In-vivo & In-vitro Study

Status

UNKNOWN

Phases

Phase 1

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02001311

Enrollment

Registered

2013-12-04

Start date

2014-01-31

Completion date

2014-06-30

Last updated

2013-12-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dental Caries, Orthodontic Appliance Complication

Keywords

chlorhexidine gel, orthodontic brackets, orthodontic patients, bacterial count, friction

Brief summary

This study investigates the benefit of using chlorhexidine gel as an antimicrobial agent in orthodontic patient to reduce caries risk and the possible consequential effect of this use on the orthodontic brackets used for the treatment. The investigators hypothesis is that chlorhexidine gel use can reduce caries risk in orthodontic patients with out causing damage to the bonded ceramic or metal orthodontic brackets.

Interventions

DRUGChlorhexidine gluconate

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

PREVENTION

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 30 Years

Healthy volunteers

Yes

Inclusion criteria

* Patients' age range from 18-30 years. * Fixed orthodontic treatment. * All the patients are at the end of leveling and alignment stage. * Initial bacterial count indicates high caries risk. * All patients will be given good oral hygiene instruction at the first visit. * The subjects had not taken antibiotics for at least 6 weeks before saliva sampling or during the experimental period. * All subjects used a fluoride dentifrice twice a day.

Exclusion criteria

* Patients' age more or less then the age range specified. * Removable orthodontic treatment. * Patients at early stages of leveling and alignment. * Initial bacterial count indicates low caries risk. * Subjects that have taken antibiotics for at least 6 weeks before saliva sampling.

Design outcomes

Primary

Measure	Time frame	Description
mutants streptococcus count	48 hours	measures the change in bacterial count before and after application of the gel

Secondary

Measure	Time frame	Description
friction	2 minutes	measures static and dynamic friction in Newton

Contacts

Primary ContactMona A Abbassy

monaabbassy@gmail.com0096658349507

Backup ContactAhmed S Bakry

drahmedbakry@gmail.com00966593944171

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026