Effect-site Concentration of Remifentanil for Blunting Hemodynamic Responses to Double-lumen Endobronchial Intubation

Comparison of the Effect-site Concentration of Remifentanil for Blunting Hemodynamic Responses to Ordinary Tracheal and Double-lumen Endobronchial Intubation During Propofol-remifentanil Total Intravenous Anesthesia

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02001285

Enrollment

Registered

2013-12-04

Start date

2013-10-31

Completion date

2015-09-30

Last updated

2013-12-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intubation, Intratracheal

Keywords

remifentanil

Brief summary

The purpose of this study is the comparison of the effect-site concentration of remifentanil for blunting hemodynamic responses to ordinary tracheal and double-lumen endobronchial intubation during propofol-remifentanil total intravenous anesthesia.

Interventions

DRUGRemifentanil

During intubation, remifentanil will be infused to prevent change arterial blood pressure and heart rate.

Study design

Allocation

NON_RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 60 Years

Healthy volunteers

Inclusion criteria

* Adult patient who is needed intubation for general anesthesia

Exclusion criteria

* patient who is anticipating difficult airway * patient who takes any drug to influence this study * cardiovascular disease, renal disease, liver disease

Design outcomes

Primary

Measure	Time frame	Description
arterial blood pressure	Change from baseline in arterial blood pressure at intubation period	Arterial blood pressure will be recorded before anesthesia, after propofol infusion, after remifentanil infusion and after intubation during 3 min with 1 min interval.

Secondary

Measure	Time frame	Description
heart rate	Change from baseline in heart rate at intubation period	Heart rate will be recorded before anesthesia, after propofol infusion, after remifentanil infusion and after intubation during 3 min with 1 min interval.

Countries

South Korea

Contacts

Primary ContactHyun Jung Kim, MD, PhD

hjanesthesia@empas.com82-64-717-2026

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026