Efficacy of Epidural Steroid for Controlling Pain After Primary TKA

Efficacy of Epidural Steroid in Controlling Postoperative Pain After Primary Total Knee Arthroplasty: A Randomized Double-blinded Controlled Trial

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02001259

Enrollment

108

Registered

2013-12-04

Start date

2014-01-31

Completion date

2015-10-31

Last updated

2017-05-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Pain

Keywords

post-operative pain control, total knee arthroplasty, epidural steroid injection

Brief summary

The purpose of this study is to determine efficacy of epidural steroid for postoperative pain control after TKA

Detailed description

Epidural triamsinolone can reduce postoperative pain and longer duration of pain control after TKA

Interventions

DRUGepidural triamsinolone

add drugs into catheter at 48 hr after surgery

DRUGepidural lidocaine

add into catheter at 48 hr after surgery

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

TRIPLE (Subject, Caregiver, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

50 Years to 85 Years

Healthy volunteers

Inclusion criteria

* osteoarthritis of the knee who undergoing unilateral primary total knee arthroplasty * 50-85 years old * ASA class 1-3

Exclusion criteria

* unable to perform epidural anaesthesia * history of drug allergies: lidocaine, steroid * renal impairment (CrCl \<30 mL/min) * liver impairment * cognitive function disorders * displacement of epidural catheter

Design outcomes

Primary

Measure	Time frame	Description
post-operative pain	3 months	measured with VAS for pain (VAS at rest and on motion)

Secondary

Measure	Time frame	Description
functional knee score	3 months	measured with WOMAC

Other

Measure	Time frame
complication of epidural triamcinolone	2 weeks
range of motion of the knee	3 months

Countries

Thailand

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026