Glaucoma
Conditions
Keywords
Water drinking test, trabeculectomy, tube shunt
Brief summary
A test that was common in the 1960's and was used to detect primary open angle glaucoma was the water drinking test (patients drank 1 quart of water to stress the fluid drainage mechanism of the eyes. Intraocular pressure was then measured over the next hour). Recently this test has been demonstrated as a predictor of peak eye pressure during the day. The purpose of this study is to compare the results of the water drinking test between eyes that have undergone trabeculectomy and eyes that have undergone tube shunt surgery.
Interventions
PROCEDUREWater Drinking Test
The Water Drinking test has been identified as a reliable and safe tool to predict maximum intraocular pressure values during a diurnal tension curve and to assess the efficacy of surgical interventions. Participants are asked to drink 10 ml/kg water (or approximately 0.33 ounces of water for every 2.2 pounds of weight or about 2.5 cups for a 150 lb. individual) over 15 minutes. Intraocular pressure is assessed every 15 minutes for one hour.
Sponsors
Wills Eye
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
21 Years to 90 Years
Healthy volunteers
No
Inclusion criteria
* prior trabeculectomy or tube shunt for the treatment of glaucoma * age 21-90 years
Exclusion criteria
* inability to give informed consent * current ocular infection * more than 1 prior trabeculectomy, or more than 1 prior tube shunt * previous refractive surgery * pregnant women * heart failure * renal failure or uncontrolled urine retention * corneal abnormalities preventing reliable IOP measurement
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Intraocular Pressure (IOP) | 1 hour | IOP is assessed every 15 minutes for one hour after the water drinking test is complete. |
Countries
United States
Outcome results
None listed