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NEAT - Prevention and Treatment of Overweight and Obesity.

Non-exercise Activity Thermogenesis (NEAT) - Prevention and Treatment of Overweight and Obesity

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT01997970
Acronym
InphactUm
Enrollment
80
Registered
2013-11-28
Start date
2014-02-28
Completion date
2015-12-31
Last updated
2016-05-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Overweight, Obesity

Keywords

NEAT, Treadmill desk

Brief summary

This study will investigate the effect on Non-exercise Activity Thermogenesis (NEAT) when implementing active workstation at offices compared to conventional office work. The primary hypothesis is that this implementation will lead to a significant increase in time spent walking per day.

Detailed description

NEAT consists of the energy expenditure of the physical activities that are non sporting-like and that we perform in our everyday life, such as walking, cleaning, shoveling snow etc. Which occupation we have play a big role in how much we are able to active our NEAT during our days and those who have more active jobs can expend up to 1500kcal more per day than those with sedentary jobs. This study aims to try and increase NEAT at offices where sedentary time often is high. Participants will be randomized to either an intervention group or to a control group. Participants in the control group will continue to work at their regular desk, but will receive an individual health talk in the beginning of the study where diet and physical activity recommendations will be discussed.Participants in the intervention group will receive the same individual health talk and a treadmill desk, which they will use for 12 months at self-selected speed. They will be recommended to walk on the treadmill for at least 1 hour per day.

Interventions

The intervention group will receive a treadmill workstation for 12 months. They will use this at self-selected speed and will be recommended to use this for at least 1 hour per day. Participants in the control group will continue with conventional office work at their regular desk. Participants in the intervention group will receive four boosting e-mails during the study period, in which they will be encouraged to use the treadmill.

BEHAVIORALHealth talk

Participants in both groups will receive a health talk with recommendations about diet and physical activity habits.

Sponsors

Umeå University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
40 Years to 67 Years
Healthy volunteers
Yes

Inclusion criteria

* Office workers with mainly sedentary tasks * BMI 25-40

Exclusion criteria

* Severe depression and/or anxiety * Exhaustion disorder * Diabetes Mellitus * Severe cardiovascular disease * Severe kidney disease * Musculoskeletal disorders that prohibit walking on a treadmill * Contraindications for physical activity * Thyroidea illness * Pregnancy For fMRI-study, additional

Design outcomes

Primary

MeasureTime frameDescription
Change from baseline in physical activity and sedentariness at 12 monthsBaseline, 12 monthsMeasured with an accelerometer (ActiGraph) and an inclinometer (ActivPAL).

Secondary

MeasureTime frameDescription
Change from baseline in anthropometrics at 12 monthsBaseline, 12 monthsLength, height, weight, waist circumference, hip circumference, sagittal height, pulse, blood pressure.
Change from baseline in body composition at 12 monthsBaseline, 12 monthsMeasured with Dual X-Ray Absorptiometry (DXA)
Change from baseline in musculoskeletal pain at 12 monthsBaseline, 12 monthsMeasured with the Chronic Pain Grade Questionnaire
Change from baseline in stress at 12 monthsBaseline, 12 monthsMeasured by assessing cortisol levels in the saliva at 4 time points during one day. Also measured with the stress- and energy scale.
Change from baseline in metabolism at 12 monthsBaseline, 12 monthsMetabolism: 2h glucose tolerance test. lipids, Hb1Ac
Change from baseline in Quality of Life at 12 monthsBaseline, 12 monthsMeasured with 2 questions from the SF-36.
Change from baseline in cognitive Function and functional brain response at 12 monthsBaseline, 12 monthsMeasured with a cognitive test battery and functional MRI (fMRI). Levels of Brain-Derived Neurotrophic Factor (BDNF) is measured in the plasma.
Qualitative interview study12 monthsParticipants will be interviewed about experiences from being part of the study and about attitudes and factors that influences them to be physically active.
Change from baseline in depression/anxiety at 12 monthsBaseline, 12 monthsMeasured with the Hospital Anxiety and Depression Scale.

Countries

Sweden

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 17, 2026