Craniosynostosis Repair, Untethering of Cord
Conditions
Brief summary
Postoperative pain is a major concern in routine management of children admitted to pediatric intensive care treatment. There are significant negative physiological and psychological ramifications of postoperative pain such as impairment of cardiac function due to tachycardia, restlessness in an intubated patient requiring increase dosage of sedative and paralytic drugs and reduced patient cooperation in the healing process. The main body of evidence dealing with gender differences in pain perception and treatment stems from studies in the adult and adolescent population as the gonadal hormones have a central role in the way one experiences pain The hypothesis of this study is that there is a difference in the perception of pain, the amount of analgesia used and the response to pain medication between male and female infants undergoing craniosynostosis repair or untethering of cord.
Interventions
None listed
Sponsors
Tel-Aviv Sourasky Medical Center
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
No minimum to 1 Years
Healthy volunteers
No
Inclusion criteria
All infants 0-1 year old, admitted to PICU after craniosynostosis repair or untethering of cord.
Exclusion criteria
1. Contraindication to analgesic medication 2. Infants with neurologic deficits that may hinder the assessment of pain severity such as facial nerve palsy and limb paralysis. 3. Ventilated infants.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The average amount per kg of analgesic medications in male and female infants 0-1 year old. | The first 24h after surgery |
| The average reduction in pain severity score after receiving analgesics in male and female infants. | 24h after surgery |
Outcome results
None listed