Risk Factors for Development of Rapid Cycling in Bipolar Disorder Patients

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01992302

Enrollment

289

Registered

2013-11-25

Start date

2004-06-30

Completion date

2013-11-30

Last updated

2013-11-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bipolar Disorder

Keywords

Rapid cycling

Brief summary

In this study we tried to elucidate the factors associated with the development of a rapid cycling course in bipolar disorder patients, in a prospective and longitudinal design, and the role of antidepressants. The identification of risk factors is extremely relevant from the clinical point of view. We hypothesized that rapid cycling bipolar disorder is associated with more chronicity, poor outcome, and more antidepressant prescription.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Inclusion criteria

* Bipolar I and II disorder patients according to DSM-IV criteria

Exclusion criteria

* Major medical comorbidities, voluntary drop-out from study

Design outcomes

Primary

Measure	Time frame
Number of patients who develop rapid cycling	8 years

Secondary

Measure	Time frame
Factors associated with the development of a rapid cycling course in bipolar disorder patients	8 years

Countries

Spain

Outcome results