Laryngomalacia, Stridor
Conditions
Keywords
stridor, laryngomalacia, ultrasound
Brief summary
The hypothesis of the study is that laryngeal US can accurately and reliably diagnose laryngomalacia in infants with congenital stridor. Stridor is a respiratory noise caused by partial obstruction of the large airways at the level of the pharynx, larynx and/or trachea. The most prevalent congenital cause of stridor is laryngomalacia. Flexible laryngobronchoscopy (FLB) under sedation is regarded as the gold standard. However, FLB under sedation has some drawbacks as it requires venous access, use of sedative agents, may cause discomfort for the patient and is costly. Ultrasound (US) is a noninvasive, painless, radiation free, well tolerated imaging technique. It allows for dynamic assessment of moving structures in an awake patient and the results can be easily displayed and recorded.
Interventions
OTHERlaryngeal ultrasound
Sponsors
Tel-Aviv Sourasky Medical Center
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
DIAGNOSTIC
Masking
DOUBLE (Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
No minimum to 12 Months
Healthy volunteers
No
Inclusion criteria
Infants referred for FLB and bronchoscopy due to congenital stridor at the Department of Pediatric Pulmonology, Critical Care and Sleep Medicine at the Tel Aviv Sourasky Medical Centre
Exclusion criteria
* Prior knowledge of the cause for stridor * History of foreign body aspiration
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The yield of US in diagnosing laryngomalacia in comparison to FLB. | December 2013- January 2015 (13 months) |
Secondary
| Measure | Time frame |
|---|---|
| The yield of US in diagnosing other causes of congenital stridor compared to FLB. | December 2013- January 2015 (13 months) |
Outcome results
None listed