Molecular Characteristics of the Persistent Intestinal Fistulae After Glue Application

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01990833

Enrollment

Registered

2013-11-25

Start date

2012-01-31

Completion date

2013-03-31

Last updated

2013-11-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Enterocutaneous Fistulas

Brief summary

For non-healing ulcers, abnormal periods of wound healing processes: inflammation, proliferation and remodelling, are believed to lead to chronic wounds. As a chronic stalled wound, investigators hypothesized that these glue-assisted closure (GAC)-failed enterocutaneous fistula (ECF) might have a prolonged inflammatory phase modulated by excessive pro-inflammatory cytokines or proteases. The aim of this study was to analyze the chemicals in ECF wounds in order to determine patients' condition and fitness for GAC.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Inclusion criteria

* above 18 years old; * single tubular (tract length \>2 cm) ECF; * low output volume (\<200 ml/24h);

Exclusion criteria

* fistulas of cancer-infiltrated; * associated abscess; * foreign bodies; * distal bowel obstruction;

Design outcomes

Primary

Measure	Time frame	Description
Fistula closure after glue application	7 days	No fistula output

Outcome results