Swiss Kidney Stone Cohort (SKSC)

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01990027

Acronym

SKSC

Enrollment

1250

Registered

2013-11-21

Start date

2014-04-30

Completion date

2024-04-30

Last updated

2017-11-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Kidney Stone

Keywords

kidney stone

Brief summary

The SKSC is a continuous database with the objective of a standardized diagnosis and monitoring of patients with kidney stones as well as the establishment of a Biobank.

Detailed description

The objective of this study is multi-site, standardized observation and characterization of kidney stone patients. Furthermore, an adequate structure should be established for the execution of studies with kidney stone patients, in order to then, if necessary, develop recommendations for useful monitoring or prophylactic measures, as well as new treatment options for kidney stone patients. A control group of 250 stone-free volunteers matching patients cohort participants for sex and age started recruitment in October 2017 and will serve the purpose of comparison in future studies.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

For SKSC Patients Group: Inclusion Criteria: Only patients that meet all of the following inclusion criteria can be included in this study: * Signed Declaration of informed consent * Male or female * Recurrent kidney stone episodes (more than 1) or an individual kidney stone episode with one or several of the following risk factors: * The first manifestation at the a minimum age of 25 * Positive family history * Non-calcium oxalate stones * Gastrointestinal disorders (e.g. gastric bypass surgery, inflammatory bowel disease, malabsorption etc.) * Osteoporosis * Nephrocalcinosis * Single kidneyness * Currently pregnant * Gout * Metabolic syndrome ( Diabetes Mellitus type I and II ) * Residual calculi (at least 3 months after the therapy) * Bilateral or multiple stones * Chronic urinary tract infection * Chronic renal failure (eGFR lower than 60 ml/min.) * Kidney transplant

Exclusion criteria

Patients with at least one of the following

Design outcomes

Primary

Measure	Time frame	Description
Epidemiological characterization	10 years	Epidemiological characterization of kidney stone patients

Countries

Switzerland

Contacts

Primary ContactOlivier Bonny, MD-PhD

Olivier.Bonny@unil.ch

Backup ContactCarsten Wagner, MD

Outcome results