Antibiotic Resistant Infection
Conditions
Keywords
colonization
Brief summary
The purpose of this study is to determine 2% chlorhexidine wipes are effective in preventing of colonization of multi-drug resistant bacteria in intensive care unit patients.
Detailed description
The purpose of this study is to evaluate the usefulness of bathing with chlorhexidine wipe to reduce the risks of multidrug resistant bacteria acquisition and hospital-acquired bloodstream infection among ICU patients
Interventions
DRUG2% chlorhexidine wipe
The ICU patients will be bathing with 2% chlorhexidine wipe
DRUGSoap
The ICU patients will be bathing with Soap
Sponsors
Mahidol University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 95 Years
Healthy volunteers
No
Inclusion criteria
* Age \> 18 years * Admission in critical care unit eg. ICU, respiratory care unit, Cardiac care unit with in 24 hours * Expected duration of critical care unit admission \> 48 hours
Exclusion criteria
* History of chlorhexidine allergy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The overall rate of Multidrug resistant bacteria acquisition at 7 days after received 2% chlorhexidine wipe bathing versus with soap bathing | 7 days after recieved 2% chlorhexidine wipes | 7 days after received 2% chlorhexidine wipes,the microbiology laboratory will process surveillance specimens using either standard culture-based at both nostrils, axillar, groins, rectum |
Secondary
| Measure | Time frame |
|---|---|
| The overall rate of hospital-acquired bloodstream infections per 1000 patient-days with chlorhexidine wipe bathing versus with soap bathing | 48 hours after recieved 2% chlorhexidine wipes |
Countries
Thailand
Outcome results
None listed