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Cadence and Intensity in Children and Adolescents (CADENCE-KIDS)

Cadence and Intensity in Children and Adolescents (CADENCE-KIDS)

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT01989104
Enrollment
123
Registered
2013-11-20
Start date
2013-12-31
Completion date
2017-04-30
Last updated
2022-12-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy

Keywords

Indirect calorimetry

Brief summary

The purpose of this study is to measure and link cadence (number of steps taken in a minute) to intensity of physical activity (e.g., low-intensity, moderate-intensity, vigorous-intensity) in children and adolescents (6-20 years-old), and to identify the cadence values corresponding to children's and adolescent's behavior during simulated free-living activities.

Detailed description

Procedure - 1 visit - (approximately 3 hours in total) Day of Testing: Participant must be FASTED - No food for 4 hours before visit. All of the study procedures involving the participant will be completed in a single testing session (one-day - approximately 3 hours) at the Pennington Biomedical Research Center. If preferred, two visits on separate days can be scheduled to complete the protocol. * Screening questions (approximately 3-5 minutes) o Participants (or their legal guardian) will be asked to answer several screening questions to determine their eligibility for participating in CADENCE-KIDS. * Height and weight measures data collection (approximately 10 minutes) * Height will be measured. * Body weight and body fat percentage will be measured using a specialized scale. * Waist circumference will then be measured using a measuring tape. * Instrument attachment, treadmill walking, free-living activities (approximately 140 minutes) * Participants will be fitted with 10 devices (Digi-Walker Pedometer, NL-1000 Pedometer, StepWatch Activity Monitor, SenseWear Armband, GT3X+ accelerometer, GENEActiv Accelerometer, Actical Accelerometer, ActivPal Accelerometer, Polar Heart Rate Monitor, K4b2 Portable Metabolic Unit) to measure/monitor physical activity throughout the testing session. * Participants will then complete several low intensity free-living activities while their physical activity and oxygen uptake are concurrently assessed. Specifically, participants will rest in a chair, watch a portion of a child-friendly movie while seated in a chair, and color in a coloring book while seated in a chair. Each activity will last for 5 minutes and a 2 minute rest will occur between each activity. * Participants will then complete a series of walking bouts on a treadmill while their physical activity and oxygen uptake are concurrently assessed. The walking bouts start at 0.5 miles per hour and end at 5 miles per hour (0.5 miles per hour increments). Treadmill testing stops when the participant finishes the bout where they naturally select to jog/run, or following the completion of the last bout at 5.0 miles per hour, whichever occurs first. A 2 minute rest will occur between each treadmill bout. * Participants will then complete three additional free-living activities where physical activity and oxygen uptake continue to be concurrently measured. Specifically, participants will step up and down on an aerobic step at 88 beats per minute, dribble a basketball, and perform jumping jacks at 126 beats per minute (63 jumping jacks per minute). Each activity will last for 5 minutes and a 2 minute rest will occur between each activity.

Interventions

None listed

Sponsors

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
CollaboratorNIH
Pennington Biomedical Research Center
Lead SponsorOTHER

Study design

Observational model
OTHER
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
6 Years to 20 Years
Healthy volunteers
Yes

Inclusion criteria

* 6 to 20 years of age at the time of study enrollment * Not limited in the ability to walk

Exclusion criteria

* Hospitalization for mental illness within the past 5 years. * Any condition/medication that may affect heart rate response to exercise testing. * Previous history of, or clinical symptoms or signs of, cardiovascular disease, stroke or transient ischemic attacks, chest pain, unusual dyspnea during physical activity/exercise, severe ankle edema, or intermittent claudication. * Previous history of musculoskeletal injuries or problems causing severe pain during physical activity or exercise which interferes with daily activities. * Participant has a pacemaker or other implanted medical device (including metal joint replacements). * Participant is pregnant. * Participant is unable to complete all testing (1 or two sessions, as preferred) within a maximal two week period.

Design outcomes

Primary

MeasureTime frameDescription
Cadence - Steps Per Minute1 dayCadence steps per minute represents an overlooked opportunity to describe the intensity of ambulatory activity.

Countries

United States

Participant flow

Participants by arm

ArmCount
Children Group 1
6-8 years of age
22
Children Group 2
9-11 years of age
25
Adolescents Group 1
12-14 years of age
25
Adolescents Group 2
15-17 years of age
24
Young Adults
18-20 years of age
24
Total120

Withdrawals & dropouts

PeriodReasonFG000FG001FG002FG003FG004
Overall StudyWithdrawal by Subject30000

Baseline characteristics

CharacteristicChildren Group 1Children Group 2Adolescents Group 1Adolescents Group 2Young AdultsTotal
Age, Categorical
<=18 years
22 Participants25 Participants25 Participants24 Participants0 Participants96 Participants
Age, Categorical
>=65 years
0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants
Age, Categorical
Between 18 and 65 years
0 Participants0 Participants0 Participants0 Participants24 Participants24 Participants
Race (NIH/OMB)
American Indian or Alaska Native
0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants
Race (NIH/OMB)
Asian
2 Participants1 Participants0 Participants0 Participants0 Participants3 Participants
Race (NIH/OMB)
Black or African American
9 Participants5 Participants10 Participants11 Participants7 Participants42 Participants
Race (NIH/OMB)
More than one race
0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants
Race (NIH/OMB)
Unknown or Not Reported
0 Participants0 Participants0 Participants0 Participants0 Participants0 Participants
Race (NIH/OMB)
White
11 Participants19 Participants15 Participants13 Participants17 Participants75 Participants
Region of Enrollment
United States
22 Participants25 Participants25 Participants24 Participants24 Participants120 Participants
Sex: Female, Male
Female
10 Participants13 Participants13 Participants12 Participants12 Participants60 Participants
Sex: Female, Male
Male
12 Participants12 Participants12 Participants12 Participants12 Participants60 Participants

Adverse events

Event typeEG000
affected / at risk
EG001
affected / at risk
EG002
affected / at risk
EG003
affected / at risk
EG004
affected / at risk
deaths
Total, all-cause mortality
0 / 220 / 250 / 250 / 240 / 24
other
Total, other adverse events
0 / 220 / 250 / 250 / 240 / 24
serious
Total, serious adverse events
0 / 220 / 250 / 250 / 240 / 24

Outcome results

Primary

Cadence - Steps Per Minute

Cadence steps per minute represents an overlooked opportunity to describe the intensity of ambulatory activity.

Time frame: 1 day

ArmMeasureGroupValue (MEAN)
Children Group 1Cadence - Steps Per MinuteModerate Intensity128.4 Cadence - Steps per Minute
Children Group 1Cadence - Steps Per MinuteVigorous Intensity157.7 Cadence - Steps per Minute
Children Group 2Cadence - Steps Per MinuteModerate Intensity116.5 Cadence - Steps per Minute
Children Group 2Cadence - Steps Per MinuteVigorous Intensity142.7 Cadence - Steps per Minute
Adolescents Group 1Cadence - Steps Per MinuteModerate Intensity106.6 Cadence - Steps per Minute
Adolescents Group 1Cadence - Steps Per MinuteVigorous Intensity129.3 Cadence - Steps per Minute
Adolescents Group 2Cadence - Steps Per MinuteVigorous Intensity126.3 Cadence - Steps per Minute
Adolescents Group 2Cadence - Steps Per MinuteModerate Intensity101.3 Cadence - Steps per Minute
Young AdultsCadence - Steps Per MinuteModerate Intensity87.3 Cadence - Steps per Minute
Young AdultsCadence - Steps Per MinuteVigorous Intensity129.9 Cadence - Steps per Minute

Source: ClinicalTrials.gov · Data processed: Feb 14, 2026