Risk of Central Venous Stenosis in Patients With Chronic Renal Failure After IJ Line Placement

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01988766

Enrollment

1424

Registered

2013-11-20

Start date

2012-10-31

Completion date

2014-08-31

Last updated

2014-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thrombosis

Keywords

Thrombosis, Central Venosis Catheter, Renal Disease, Vascular Access

Brief summary

The purpose of this study is to compare the difference in thrombosis as a result of internal jugular (IJ) catheters versus peripherally inserted central catheter (PICC) lines. It is hypothesized that there will be a decreased rate of thrombosis in patients as a result of IJ catheters verses PICC lines.

Detailed description

In a cohort of patients from Sept 1, 2010 until December 31, 2011 with chronic kidney disease (CKD) has shown that the incidence of IJ thrombosis after short term catheter access occurred in only 1/26 subjects or 4%. The current study is being done to compare this experience with the incidence of thrombosis from PICC lines. A secondary aim will be to determine if variables such as level of renal function, prior history of thrombosis or atherosclerosis contribute to the risk of thrombosis when PICC lines are placed. This data will provide the first comparison of the incidence of thrombotic complications from short term IJ catheter access versus PICC lines.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* subjects who had a PICC line placed at the University of Chicago between September 1, 2010 and December 31, 2011

Exclusion criteria

* subjects under the age of 18

Design outcomes

Primary

Measure	Time frame	Description
Incidence of Thrombosis	15 months	To calculate the incidence of deep venous thrombosis from PICC lines in patients

Secondary

Measure	Time frame	Description
Demographic Risk Factor Association with Risk of Thrombosis from PICC or IJ access	15 months	To evaluate if factors, known to be associated with thrombosis and atherosclerosis, are associated with the risk of thrombosis from PICC or IJ access. These factors include: renal failure, diabetes, hypertension, cancer, transplant, gender, age or the indication for the access, including antibiotics or chemotherapy.

Countries

United States

Outcome results