GLP-1's Effect on Cardiac Parameters and Mesenteric Blood Flow

GLP-1's Influence on Intestinal Blood Flow

Status

Completed

Phases

Unknown

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01988545

Enrollment

Registered

2013-11-20

Start date

2013-11-01

Completion date

2014-12-01

Last updated

2026-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy

Keywords

GLP-1, blood flow, cardiac out put, stroke volume, beat to beat, effect of GLP-1 on cardiac parameters and blood flow

Brief summary

to investigate the effect of the human incretin hormone GLP-1 on mesenteric blood flow and cardiac parameters

Detailed description

to investigate the effect of the human incretin hormone GLP-1 on mesenteric blood flow and cardiac parameters, in healthy subjects, 4 arms, task force monitor

Interventions

OTHER1,5 nmol/kg,GLP-1 sc injection

OTHER1,5 nmol/kg GLP-1 9-36amide, sc injection

OTHERExendin-4 ;10 ug,sc injection

OTHERsaline

Study design

Allocation

RANDOMIZED

Intervention model

SINGLE_GROUP

Primary purpose

BASIC_SCIENCE

Masking

DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

20 Years to 80 Years

Healthy volunteers

Yes

Inclusion criteria

* healthy subjects

Exclusion criteria

* medical conditions

Design outcomes

Primary

Measure	Time frame	Description
blood flow	with in 120 minutes	blood flow change measured by ultra sound

Countries

Denmark

Contacts

PRINCIPAL_INVESTIGATORLasse Bremholm, MD, ph.d.

Køge Hospital

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Sep 16, 2026