Area Under Curve [N06.850.520.830.200]
Conditions
Brief summary
Postprandial glycaemic control is an important risk factor for the development of type 2 diabetes, cardiovascular disease and all-cause mortality. Previous research has demonstrated that exercise performed in the postprandial state paradoxically results in a deterioration in glucose tolerance in the immediate post-exercise period (Gonzalez et a. 2013; Gonzalez and Stevenson 2013). This study aims to assess the timecourse of this post-exercise effect.
Interventions
BEHAVIORALExercise
Exercise at 55% of maximum power output for 30 min.
BEHAVIORALRest
Rest for 30 min
BEHAVIORALDelay
Delay between exercise and OGTT
Sponsors
Northumbria University
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE
Masking
NONE
Eligibility
Sex/Gender
MALE
Age
18 Years to 40 Years
Healthy volunteers
Yes
Inclusion criteria
* Normal weight (18-25 kg/m2) * Physically active (\>or= 3 times per week) * Male
Exclusion criteria
* Contraindications to exercise * Food intolerances * Food allergies
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Postprandial glucose concentration area under the curve | 90 min | Blood glucose concentrations will be sampled every 15 min following an oral glucose tolerance test. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Postprandial insulin concentration area under the curve | 90 min | Insulin concentrations will be determine every 15 min following an oral glucose tolerance test. |
Countries
United Kingdom
Outcome results
None listed