Infertility
Conditions
Keywords
IVF , embryo implantation, HCG
Brief summary
The endometrium is deprived of signals form the embryo in IVF conditions. Studies suggest that placing HCG into the uterus prior to embryo transfer can enhance implantation.
Detailed description
The study is in pilot phase, uncontrolled. The risks appear to be minimal and there are conflicting new reports being announced. A small amount of fluid with HCG is injected into the uterus. HCG is a potent signal to the uterus for preparation for implantation. This is not a funded study. Three published studies suggest the approach is valid; one refutes the concept.
Interventions
DRUGHCG is introduced
must have good blastocysts
Sponsors
Servy Massey Fertility Insititute
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
21 Years to 47 Years
Healthy volunteers
Yes
Inclusion criteria
\- infertility patients undergoing IVF with good expectation of two embryos day 3 or day 5. must speak and read English. Includes donor eggs.
Exclusion criteria
abnormal uterus \-
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| HCG enhances pregnancy rate | 9 months. | compare pregnancy rates to established clinical norms. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| implantation rate | 18 months | compare implantation rate per embryo to clinical norms. |
| ongoing pregnancy rate | 22 months | compare success to clinical norms |
Countries
United States
Outcome results
None listed