Salty Taste, Spicy Diet
Conditions
Keywords
Salty taste, Urinary sodium excretion, Spicy hedonic, Blood pressure
Brief summary
Excess dietary salt intake is closely associated with the development of hypertension and cardiocerebral vascular diseases. Reduction in high salt intake significantly prevents hypertension and cardiocerebral events. Currently, few promising method is available to reduce salt intake in human. This study focus on examining the salty taste in population-level and exploring whether dietary factors can reduce salt intake through acting on salty taste.
Detailed description
Hypertension and its related complications are common health problems that can lead to multiple organ damage and death. Excessive salt intake plays very important role in the development of hypertension. Reducing salt intake prevents high blood pressure as well as cardiocerebral vascular diseases. The experimental design is a multi-center, random-order, double-blind observational study to investigate the salty taste and salt intake in population-level. A total of 606 individuals from four cities in China are recruited in this study. This study aims to explore the salty taste characterization and salt intake in participants who like or dislike spicy diet through questionnaire, spicy preference, salty perception and super-threshold as well as the 24-hour urinary sodium excretion.
Interventions
OTHERNo Intervention
Sponsors
Zhiming Zhu
Study design
Observational model
ECOLOGIC_OR_COMMUNITY
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to 55 Years
Healthy volunteers
Yes
Inclusion criteria
* Age ≥ 18 years and ≤ 55 years. * Willing and able to provide written informed consent. * Willing and able to comply with all study procedures.
Exclusion criteria
* Hypogeusia or loss due to neural system disease or oral and digestive disease. * Capsaicin allergy and poor compliance. * Recently oral diuretics and participate in other pharmacological experiment in 3 months. * Acute infection, cancer, serious arrhythmias, drug or alcohol abuse. * Currently have cold, fever, acidosis, dehydration, diarrhea, vomiting during the study. * Unwilling or unable to communication due to the dysnoesia and language disorders * Severe neural or psychiatric diseases that would preclude fully understand and corporation in the study. * Pregnancy or lactation * Unwilling to sign the informed consent
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Effects of spicy diet on salt taste | Day 1 | Daily spicy food intake was evaluated by diet questionnaire and salty taste was tested through salt perception and super-threshold examination on the first day when the participant was investigated. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Effects of spicy diet on salt intake | Day 1 | Daily spicy food intake was evaluated by diet questionnaire on the first day when the participant was investigated and then 24-hour urine was collected during the following day and salt intake was assessed by 24-hour urinary sodium excretion. |
| Effects of spicy diet on obesity parameters. | Day 1 | Daily spicy food intake was evaluated by diet questionnaire and body mass index and waist circumference were measured on the first day when the participant was investigated. |
| Effects of spicy diet on blood pressure | Day 1 | Daily spicy food intake was evaluated by diet questionnaire and systolic and diastolic blood pressure were measured on the first day when the participant was investigated. |
Countries
China
Outcome results
None listed