Esophageal Stump Washout

Esophageal Stump Washout Reduces Free Intraluminal Tumor Cells During Resection of Carcinomas of the Esophagus and Cardia

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01980394

Enrollment

Registered

2013-11-11

Start date

2004-05-31

Completion date

2013-12-31

Last updated

2016-02-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Esophageal Cancer, Gastrooesophageal Cancer

Keywords

esophagus, gastro-esophegeal junction, cancer, tumor seeding, free viable tumor cells, surgery, intraluminal tumor cells, stump washout

Brief summary

Intraluminally shed viable tumor cells might contribute to local recurrence in cancer of the esophagus and the cardia. The aim of the the study was to establish a method of mechanical lavage of the remaining part of the esophagus and, hence, to reduce the intraluminal cancer cells before doing the esophageal anastomosis.

Detailed description

See study protocol!

Interventions

PROCEDUREEsophageal Stump Washout

a washout of the closed esophageal stump with Ringer-solution (10 times 30ml) is performed by means of a transorally inserted 24F-Foley catheter. The first, fifth and tenth portion of the lavage fluid are collected and sent to cytological examination

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 95 Years

Healthy volunteers

Inclusion criteria

* histologically confirmed cancer of gastro-esophageal junction with indication for surgery

Exclusion criteria

* missing informed consent

Design outcomes

Primary

Measure	Time frame
Presence of intraluminal tumor cells in the remaining oesophageal stump	during the operation

Countries

Switzerland

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026