0.15 mg Spinal Morphine vs. no Treatment for Morphine Requirement After VATs.

The Comparison of 0.15 Milligram Spinal Morphine vs.no Treatment for Morphine Requirement After Video-assisted Thoracoscopic Surgery. A Pilot Randomized Control Study

Status

UNKNOWN

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01979354

Enrollment

Registered

2013-11-08

Start date

2014-02-28

Completion date

2016-12-31

Last updated

2015-11-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Pain

Keywords

spinal morphine, VATs lobectomy

Brief summary

Postoperative pain after Video-assisted Thoracoscopic Surgery (VAT) is still debating. Therefore the investigators conduct a study comparing 0.15 mg spinal morphine and control group in term of analgesia.

Interventions

DRUGSpinal morphine

0.15 mg spinal morphine

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Age 18 year or over * Patient ASA physical status I-III. * Scheduled for video-assisted thoracoscopic lobectomy or blebectomy with pleurectomy or pleural abrasion * Can operate a patient-controlled analgesia (PCA) device.

Exclusion criteria

* Known hypersensitivity to morphine * History of bleeding tendency. * Known case of infection at the back * Patient refuse for spinal anesthesia * History of cerebrovascular disease. * Need mechanical ventilatory support during postoperative period

Design outcomes

Primary

Measure	Time frame
Total morphine requirement in 48 hours	48 hours

Secondary

Measure	Time frame
Pain	48 hours

Countries

Thailand

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026