Glycaemic Load and Pre-meal Insulin Doses in Type 1 Diabetes Patients

Use of the Glycemic Load for the Adjustment of the Dose of Preprandial Insulin in Patients With Type 1 Diabetes Mellitus in Insulin Pump Therapy

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01978704

Acronym

GLUT

Enrollment

Registered

2013-11-07

Start date

2013-02-28

Completion date

2013-08-31

Last updated

2013-11-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 1 Diabetes

Brief summary

The aim of this study is to compare the feasibility and the efficacy on short-term glucose control of pre-meal insulin doses adjustment made on the bases of the glycemic load or of the carbohydrates content of the meal in patients with type 1 diabetes mellitus treated with insulin pump

Interventions

OTHERAdjustment of pre-prandial insulin doses on the bases of glycaemic load of the meal

OTHERAdjustment of pre-prandial insulin doses on the bases of carbohydrates content of the meal

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Inclusion criteria

* Type 1 diabetes treated by insulin pump

Exclusion criteria

* Preganncy * HbA1c \> 9% * Any serious acute or chronic illness a part diabetes

Design outcomes

Primary

Measure	Time frame
daily plasma glucose excursion	1 week
mean plasma glucose concentrations	1 week

Secondary

Measure	Time frame
postprandial plasma glucose concentrations	1 week

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026