Exercise Performance in Copd Patients
Conditions
Keywords
COPD exercise inflammation prednisone
Brief summary
The objective of this study is to investigate if there is an effect on exercise performance og of the anti inflammatory drugs prednisone and solu-medrol in patints with chronic obstructive pulmonary disease(COPD)
Detailed description
RCT study with 4 days of steroid
Interventions
DRUGprednisone
similar size tablets
Sponsors
Bispebjerg Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
DOUBLE (Subject, Investigator)
Intervention model description
RCT study with steroid.
Eligibility
Sex/Gender
MALE
Age
40 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
FEV1\< 60% FEV1/FVC ratio \<70 % * able to use a ergometer bike
Exclusion criteria
Haemodynamicaly unstable heart conditions * exacerbations before 6 week entry of the study exacerbation during the study period treatment with beta blockers malignancy the last 5 years allergi toward IMP
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| effect on muscle power | jan 2013 to july 2013 (6 months) | muscular strenght |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| the inflammatory response | jan 2013 to july 2013 (6 months) | hsCRP |
Other
| Measure | Time frame | Description |
|---|---|---|
| vo2max | jan 2013 to july 2013 ( 6 months) | fitness |
| VO2max | jan 2013 until july 2013 (6 months) | fitness |
Countries
Denmark
Outcome results
None listed