Knee Arthritis Disease
Conditions
Keywords
total knee arthroplasty, lumbar plexus block, stimulating catheters, peripheral nerve blocks
Brief summary
Stimulating catheters have been introduced to reduce the incidence of secondary failure after continuous peripheral nerve blocks, but they effectiveness over traditional nonstimulating catheters is still controversial. Furthermore no volume-response study has compared the success rates of the two techniques for continuous lumbar plexus block. The aim of this prospective, randomized, blinded study is to detect if stimulating catheters decrease the minimal effective volume (MEAV) of 1.5% mepivacaine required for successful lumbar plexus block (LPB) in 50% of patients compared with conventional non-stimulating catheters.
Interventions
DEVICEstimulong 100, pajunk, germany
simulating catheter
DEVICEplexolong 100, pajunk, germany
nonstimulating catheter
Sponsors
ASST Gaetano Pini-CTO
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* patients undergoing total knee arthroplasty
Exclusion criteria
* diabetes * coagulation disorders * allergy to local anesthetic
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| minimum effective anesthetic volume in 50% of patients | thirty minutes after local anesthetic injection |
Secondary
| Measure | Time frame |
|---|---|
| morphine requirement | intraoperatively |
Countries
Italy
Outcome results
None listed