Peritonitis and Loss of Residual Renal Function, Technique Failure and Mortality in Peritoneal Dialysis Patients

The Role of Peritonitis in the Loss of Residual Renal Function, Technique Failure and Mortality in Peritoneal Dialysis Patients

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01977716

Enrollment

350

Registered

2013-11-07

Start date

2013-12-31

Completion date

2016-01-31

Last updated

2013-11-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Loss of Residual Renal Function, Technique Failure in Peritoneal Dialysis

Keywords

Peritonitis, loss of residual renal function, technique survival

Brief summary

The primary objective is to analyze peritonitis rate and peritonitis bacteriology as risk factors for loss of residual renal function, technique failure and mortality in chronic kidney disease patients. Secondary objectives are: To know the current rate of peritonitis in peritoneal dialysis population and to understand the bacteriological profile of peritonitis. To know the rate and risk factors other than peritonitis involved in the loss of residual renal function. To analyze the utility of alternative diagnostic tests, such as reagent strips, for early detection of peritonitis when traditional tests are not available. To analyze the simultaneous measurement of serum creatinine and cystatin-C as alternative measurements of peritoneal clearance and residual renal function.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

Inclusion criteria include: adult patients with signed informed consent given; there should not be selection for age, gender, primary cause of renal disease. \-

Exclusion criteria

Patients will not be included if they were previously in hemodialysis or received renal transplant. Patients will also be excluded if they are on immunosuppressive therapy, have diagnosis of cancer, or are seropositive for HIV or hepatitis. \-

Design outcomes

Primary

Measure	Time frame	Description
Loss of residual renal function	25 months	—
Technique (peritoneal dialysis) failure	25 months	Shift to hemodialysis

Other

Measure	Time frame
Death	25 months

Countries

Mexico

Contacts

Primary ContactRamon Paniagua, MD, PhD

jrpaniaguas@gmail.com+52-55-56276900

Outcome results