Stored RBC Transfusion and Immonomodulation

Infective Complication After Surgery and Transfusion of Allogenic RBC Fresh or Stored

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01976234

Enrollment

181

Registered

2013-11-05

Start date

2013-09-30

Completion date

2015-12-31

Last updated

2016-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infections

Brief summary

Transfusion of RBC is associated with post operative infections. Our hypothesis is that stored blood could be related with increased post operative infection risk. Surgical patients transfused during the operation or immediately after will be included in our study. Patients will receive fresh or old blood during the whole recovery.

Interventions

OTHERFresh RBC

Patients will receive fresh blood only

OTHEROld RBC

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

SCREENING

Masking

DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender

ALL

Age

18 Years to 85 Years

Healthy volunteers

Inclusion criteria

* Patients transfused during or in 24h after surgical operation

Exclusion criteria

* Patients transfused during the 30 days before the operation * Immunodepressed patients * Infections during the 30 days before operations * Emergency surgery

Design outcomes

Primary

Measure	Time frame
Incidence of infections	28 days

Countries

Italy

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026