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Wound-healing Improvement by Resurfacing Split-Thickness Skin Donor Sites With Thin Split-thickness Grafting

Wound-healing Improvement by Resurfacing Split-Thickness Skin Donor Sites With Thin Split-thickness Grafting

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT01974583
Enrollment
192
Registered
2013-11-01
Start date
2002-01-31
Completion date
2013-03-31
Last updated
2013-11-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Disorder of Skin Donor Site, Skin Graft Disorder, Wound Healing Disturbance of

Keywords

the split-thickness skin graft (STSG) donor site, regraft, wound healing

Brief summary

Split-thickness skin grafting remains fundamental treatment of patients with deep burns and other traumatic injuries. However, the split-thickness skin graft (STSG) donor site dressing has been controversial until now. Our study here aimed to assess patient comfort and wound-healing efficacy with the application of thin split-thickness grafting on STSG donor sites.

Detailed description

Background:Split-thickness skin grafting remains fundamental treatment of patients with deep burns and other traumatic injuries. However, the split-thickness skin graft (STSG) donor site dressing has been controversial until now. Our study here aimed to assess patient comfort and wound-healing efficacy with the application of thin split-thickness grafting on STSG donor sites. Methods: 192 consecutive patients undergoing split-thickness skin grafting were included in the study and the participants were randomly divided into three groups: Group A was regrafted with thin STSG, while, Group B and Group C were covered with the occlusive hydrocellular dressing and paraffin gauze, respectively. The three groups were compared regarding to the time of epithelialization, pain sensed by the patients and the scar formation.

Interventions

PROCEDUREregrafted with thin split-thickness skin graft

Group A (the treatment group) were regrafted with thin split-thickness skin graft

PROCEDUREcovered with the occlusive hydrocellular dressing

group B covered with the occlusive hydrocellular dressing (Allevyn Adhesive, Smith & Nephew)

PROCEDUREcovered with paraffin gauze

Group C covered with paraffin gauze

Sponsors

Tang-Du Hospital
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
5 Years to 56 Years
Healthy volunteers
No

Inclusion criteria

* patients who continuously received an STSG from January 2002 to December 2010 in Department of Burn and Plastic Surgery, Tangdu Hospital, Fourth Military Medical University

Exclusion criteria

* The patients who were significant psychiatric, hypersensitive to silver, and not be followed up were excluded

Design outcomes

Primary

MeasureTime frameDescription
The time of epithelializationup to 4 weeksThe time of epithelialization was observed every 3 days

Secondary

MeasureTime frameDescription
Pain sensed by the patientsup to 6 monthsPain sensed by the patients was assessed by Wong-Baker FACES Pain Rating Scale on day 2 and 5 after surgery

Other

MeasureTime frameDescription
Scar formation of skin donor site1 yearScar formation of skin donor sites was evaluated by Vancouver scar scale in terms of colour, vascular distribution, thickness and scratchability 6-12 months after surgery

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026