Dysphagia, Pneumonia
Conditions
Keywords
Dysphagia, Community acquired pneumonia, Mortality, Rehospitalization
Brief summary
This study investigates relationship between community acquired pneumonia and oropharyngeal dysphagia in patients admitted to a department of respiratory medicine in Northern Denmark. The endpoints will be re-hospitalisation and mortality.
Detailed description
Community acquired pneumonia (CAP) is an important cause of morbidity and mortality in elderly patients. Risk factors are many including oropharyngeal dysphagia (OD). Systematic screening of OD is recommended for at-risk popolations, however these resommandations do not specifically address elderly patients hospitalized with CAP. In this study OD is assessed in all patients by Volume-Viscosity Swallowing Test (V-VST) The study is registered by the Danish Data Protection Authority (2008-58-0028)
Interventions
OTHERDysphagia
Oropharyngeal dysphagia assessed by Volume-Viscosity Svallowing Test
Sponsors
Regionshospital Nordjylland
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Temperature \> 38 degrees Celcius * New infiltrate on chest x-ray * Increased C-reactive protein (CRP) * Either cough, dyspnea, pleuritic chest pain, expectoration, or tachypnea
Exclusion criteria
* patients referred from the intensive care unit * reduced cognitive awareness if not able to able to cooperate with the assessment of oropharyngeal dysphagia
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Intra Hospital Mortality | With in 10 days from admission | Intra hospital mortality is death while the patient is hospitalized |
| 30 Day Mortality | 30 days after discharge | Death within 30 days of discharge |
| Re-hospitalization | 30 days after discharge | The rate of re-hospitalization within 30 days of discharge |
Countries
Denmark
Participant flow
Participants by arm
| Arm | Count |
|---|---|
| Pneumonia and Dysphagia Patients with community acquired pneumonia and oropharyngeal dysphagia | 53 |
| Pneumonia Patients with community acquired pneumonia | 101 |
| Total | 154 |
Baseline characteristics
| Characteristic | Pneumonia and Dysphagia | Pneumonia | Total |
|---|---|---|---|
| Age, Categorical <=18 years | 0 Participants | 0 Participants | 0 Participants |
| Age, Categorical >=65 years | 46 Participants | 78 Participants | 124 Participants |
| Age, Categorical Between 18 and 65 years | 7 Participants | 23 Participants | 30 Participants |
| Region of Enrollment Denmark | 53 participants | 101 participants | 154 participants |
| Sex: Female, Male Female | 20 Participants | 50 Participants | 70 Participants |
| Sex: Female, Male Male | 33 Participants | 51 Participants | 84 Participants |
Adverse events
| Event type | EG000 affected / at risk | EG001 affected / at risk |
|---|---|---|
| deaths Total, all-cause mortality | 17 / 53 | 2 / 101 |
| other Total, other adverse events | 0 / 53 | 0 / 101 |
| serious Total, serious adverse events | 0 / 53 | 0 / 101 |
Outcome results
Primary
30 Day Mortality
Death within 30 days of discharge
Time frame: 30 days after discharge
| Arm | Measure | Value (COUNT_OF_PARTICIPANTS) |
|---|---|---|
| Pneumonia and Dysphagia | 30 Day Mortality | 10 Participants |
| Pneumonia | 30 Day Mortality | 2 Participants |
Primary
Intra Hospital Mortality
Intra hospital mortality is death while the patient is hospitalized
Time frame: With in 10 days from admission
| Arm | Measure | Value (COUNT_OF_PARTICIPANTS) |
|---|---|---|
| Pneumonia and Dysphagia | Intra Hospital Mortality | 7 Participants |
| Pneumonia | Intra Hospital Mortality | 0 Participants |
Primary
Re-hospitalization
The rate of re-hospitalization within 30 days of discharge
Time frame: 30 days after discharge
| Arm | Measure | Value (COUNT_OF_PARTICIPANTS) |
|---|---|---|
| Pneumonia and Dysphagia | Re-hospitalization | 10 Participants |
| Pneumonia | Re-hospitalization | 15 Participants |