Overweight and Obesity
Conditions
Brief summary
The aim of the present study is to investigate the changes in body composition and the degree of compensation to exercise induced energy expenditure after 1 year of physical activity with either moderate or vigorous intensity in overweight and class 1 obese men and women. The present study is a sub study to main study Active Commuting To Improve Well-being and Health in Everyday Life (NCT 01962259)
Interventions
BEHAVIORALPhysical activity
Sponsors
University of Copenhagen
Study design
Allocation
RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
20 Years to 45 Years
Healthy volunteers
Yes
Inclusion criteria
* Participation in main study (NCT 01962259)
Exclusion criteria
* No participation in main study
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Total body fat | Change from baseline in body fat at 3 months | Changes in total body fat (kg) measured by dual x-ray absorptiometry |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Net energy balance and degree of compensation | 3 and 6 months | 1\. Net energy balance calculated from changes in body composition, and 2. the degree of compensation as the difference between energy spent during exercise and net energy balance |
| Compensatory mechanisms | Baseline, 3 and 6 months | 1\. Resting metabolic rate determined by indirect calorimetry, 2. Total physical activity (TPA) measured using accelerometry, 3. Non-exercise activity determined as the difference between TPA and exercise activity, and 4. Energy intake determined by food records and during meal tests |
| Appetite control | Baseline, 3 and 6 months | Appetite control determined via 1. blood samples (peptides and metabolites) and 2. self rated sensations (visual analogue scales) in relation with standardized meals and exercise, as well as 3. ad libitum energy intake and 4. Eating behaviours determined via three-factor eating questionaire |
| Anthropometry | Baseline, 3 and 6 months | Body composition measured by dual x-ray absorptiometry, height, weight, waist and hip circumference, sagittal abdominal height |
Other
| Measure | Time frame | Description |
|---|---|---|
| Exercise compliance and energy expenditure | Baseline, 3 and 6 month | Exercise compliance and energy expenditure will be measured and adjusted continuously with the use of heart rate monitors over the course of the 1 year intervention |
Countries
Denmark
Outcome results
None listed