Peri-implantitis
Conditions
Brief summary
The primary objective of this study is to compare the clinical outcomes of using Er: YAG laser along with bone graft and barrier membrane to conventional mechanical debridement also with bone graft and barrier membrane in the treatment of peri-implantitis infections.
Interventions
PROCEDURELaser
This is a surgery that the patient will undergo and the laser will be used to clean the surface of the implant.
PROCEDUREMechanical debridement
This is a surgery that the patient will undergo to have the surface of the implant cleaned using hand instruments.
Sponsors
University of Michigan
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 85 Years
Healthy volunteers
Yes
Inclusion criteria
* Patients, aged 18 - 85 years * Physical status according to the American Society of Anesthesiologists (ASA) I or II, which includes patients who are systemically healthy or suffer under mild to moderate, but well controlled systemic diseases. * Patients having a minimum of 1 dental implant with peri-implantitis. * The dental implant with peri-implantitis has ≥ 3 threads exposed or pocket probing depth (PPD) ≥ 5mm, with bleeding on probing (BOP) and/or suppuration (pus). * The implants are in function for at least 6 months * No uncontrolled systemic disease or condition known to alter bone metabolism, like Osteoporosis, Osteopenia, Hyperparathyroidism, Paget's disease. * Only rough surface implant will be included in this study
Exclusion criteria
* Long-term use of antibiotics \> 2 weeks in the past two months * No peri-implantitis treatment in the last 2 months * Patients taking medications known to modify bone metabolism (such as bisphosphonates, corticosteroids, Hormone replacement therapy for menopausal women, Parathyroid hormone, Denosumab, strontium ranelate). * Pregnant females or those planning to become pregnant. * Patients with a history of medically diagnosed oral cancer, bisphosphonate usage, Sepsis or those having adverse outcomes to oral procedures in the past, will be excluded * Mobility of dental implants * History of alcoholism or drug abuse * Current smokers or quit smoking less than 6 months * Diseases of the immune system or any medical condition that may influence the outcome (uncontrolled diabetes (HbA1c \>7) * Patients with allergies known to affect one or more of the treatment provided in this study * Polish surface implants * Implants with trabecular surface
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Perio Probing Depth | Change in probing depth from beginning of study to 6 months after intervention |
Secondary
| Measure | Time frame |
|---|---|
| Bleeding on Probing | Change in bleeding on probing from beginning of study to 6 months after intervention |
Countries
United States
Outcome results
None listed