HIV
Conditions
Keywords
HIV, AIDS, PMTCT
Brief summary
The goal of the ACCLAIM (Advancing Community-Level Action for Improving MCH/PMTCT) project is to increase community demand for, uptake of, and retention in Maternal and Child Health (MCH) and/Prevention of Mother-to-child transmission of HIV (PMTCT) services to improve country progress toward elimination of pediatric HIV/AIDS.
Detailed description
This study will undertake a three-arm randomized trial in Swaziland, Uganda and Zimbabwe. Districts/regions (n=9) with 45 PMTCT-implementing health facilities and their catchment areas (populations 7300-27500), will be randomly allocated to three intervention arms: 1) community leader engagement, 2) community leader engagement with community days, or 3) community leader engagement with community days and male and female community peer groups. The primary study outcome is HIV exposed infants (HEI) returning to the health facility within two months for early infant diagnosis (EID) of HIV. Secondary study outcomes include: gestational age of women attending for first antenatal care, male partners tested for HIV, and HEI receiving nevirapine prophylaxis at birth. Changes in community knowledge, attitudes, practices and beliefs on MCH/PMTCT will be assessed through household surveys.
Interventions
BEHAVIORALCommunity leader engagement
Community leaders conducting advocacy, community dialogue and community action plans on PMTCT/MCH
BEHAVIORALCommunity days
The provision of facilitated dialogues, advocacy and education, and selected health services, to a community on a specific day
BEHAVIORALCommunity Peer Groups
Pregnant women in community peer groups receiving information and education on PMTCT/MCH through 4 weekly peer-led classes . Men in community peer groups receiving information and education on their role in supporting women and families through 4 peer-led education sessions.
Sponsors
Canadian International Development Agency
Elizabeth Glaser Pediatric AIDS Foundation
Study design
Allocation
RANDOMIZED
Intervention model
FACTORIAL
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 100 Years
Healthy volunteers
Yes
Inclusion criteria
* Must be a member of the community surveyed
Exclusion criteria
* Under 18 years of age
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Proportion of HIV-exposed infants returning to health facility HIV testing | 6-8 weeks after birth | The general objective for the study is to assess the efficacy of the three study arm activities on the uptake of, and retention of HIV positive pregnant/postpartum women in MCH/PMTCT services as measured by the proportion of infants returning to the health facility at 6-8 weeks of age for the early infant diagnosis (EID) of HIV. |
Countries
Eswatini, Uganda, Zimbabwe
Outcome results
None listed