Autologous Fat Graft Alleviate Scar Pain

Alleviation of Neuropathic Scar Pain With Autologous Fat Graft

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01970761

Enrollment

Registered

2013-10-28

Start date

2008-02-29

Completion date

2013-04-30

Last updated

2013-10-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Scar

Brief summary

Traumatic wounds inflict small- and large-fiber sensory nerve damage, causing neuropathic pain in scar tissue. Autologous fat grafting has been clinically shown to improve scar quality, but scantly study has explored its effects on pain. The aim of the study was to survey its effect on pain.

Detailed description

Methods: From February 2008 and June 2013, a total of 36 patients received autologous fat grafting in scar areas. Patients who Douleur Neuropathique 4 Questions (scores \>4/10) were enrolled this study. The Visual Analogue Scale (VAS), and Neuropathic Pain Symptom Inventory (NPSI) were used to evaluate pain preoperatively and postoperatively after 1 week, 4 weeks, and 24 weeks. The mechanism of trauma, duration of allodynia, fat graft volume, and total follow-up time were recorded.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

19 Years to 75 Years

Healthy volunteers

Inclusion criteria

* February 2008 and June 2013, patients received autologous fat grafting in scar areas and also had pain over scar area before surgery

Exclusion criteria

* patients refused to participate the study

Design outcomes

Primary

Measure	Time frame
Visual Analogue Scale (VAS)	preoperatively and postoperatively after 1 week, 4 weeks, and 24 weeks.

Secondary

Measure	Time frame
Neuropathic Pain Symptom Inventory (NPSI)	preoperatively and postoperatively after 1 week, 4 weeks, and 24 weeks

Countries

Taiwan

Outcome results