Comparison of Postoperative Aqueous Flare After 20G Versus 23G Pars Plana Vitrectomy

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01969929

Acronym

20Gvs23G

Enrollment

100

Registered

2013-10-25

Start date

2013-10-31

Completion date

2015-10-31

Last updated

2015-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Macular Hole, Macular Pucker

Brief summary

To compare postoperative inflammation and breakdown of blood-retinal barrier as measured by a laser flare-cell meter in 20G versus 23G vitrectomy.

Interventions

PROCEDURE20G Vitrectomy

PROCEDURE23G vitrectomy

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

BASIC_SCIENCE

Masking

DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

age \> 18 years macular hole macular pucker willing to perform follow up written signed consent

Exclusion criteria

other relevant eye disease: retinal detachment, provect cataract, diabetic retinopathy, AMD, relevant glaucoma, pre-surgery except for cataract surgery

Design outcomes

Primary

Measure	Time frame
Alteration of aqueous flare between preoperative and 3-week-postoperative time point	3 weeks

Secondary

Measure	Time frame
Visual acuity change	3 weeks
Closure of Macular hole	3 weeks

Other

Measure	Time frame
Patient satisfaction	3 weeks

Countries

Germany

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 23, 2026