Infertility
Conditions
Keywords
Infertility, Intrauterine insemination, Male factor infertility, Massage, Total motile sperm count
Brief summary
The purpose of this prospective, randomized study, was to determine if neck and shoulder massage performed within 15 minutes of semen sample collection will increase the semen volume, and therefore increase the total motile sperm available for insemination as a result of decreased stress.
Interventions
BEHAVIORALMassage
Sponsors
Wake Forest University Health Sciences
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
DIAGNOSTIC
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
MALE
Age
18 Years to 70 Years
Healthy volunteers
Yes
Inclusion criteria
* Infertility, * initiating clomiphene + IUI therapy * signed study consent
Exclusion criteria
* Severe male infertility (baseline semen concentration \< 10 million total motile sperm) * female bilateral tubal occlusion * failure to ovulate with clomiphene * failed clomiphene + IUI therapy (three prior cycles with no conception) * unable to tolerate clomiphene * unable or unwilling to follow study protocol
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Total Motile Sperm Count | 1 month | The primary outcome variable is total motile sperm count, which is determined based on the semen volume, concentration, and motility. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Pregnancy | 3 months | Pregnancy rate per cycle with intrauterine insemination. |
Countries
United States
Outcome results
None listed