Colorectal Cancer
Conditions
Keywords
Fast track surgery, Laparoscopic surgery, colorectal cancer
Brief summary
To compare the outcomes of fast track laparoscopic surgery and conventional laparoscopic surgery.
Detailed description
Method: This study is a blinded randomized trial. 70 patients with colorectal cancer will undergo laparoscopic colorectal resection, and will be divided into two groups. Protocols for fast-track group includes skipping preoperative mechanical bowel preparation, early restoration of diet and early postoperative ambulation. Outcome measures, length of hospital stay, postoperative surgical stress response (C reactive protein) and postoperative complications will be compared between the two groups.
Interventions
PROCEDUREfast-track surgery
Patients with colorectal cancer will undergo laparoscopic colorectal resection, and will be divided into two groups. Protocols for fast-track group includes skipping preoperative mechanical bowel preparation, early restoration of diet and early postoperative ambulation.
OTHERconventional postoperative surgery
Patients with colorectal cancer will undergo laparoscopic colorectal resection, and will be divided into two groups. Protocols for fast-track group includes skipping preoperative mechanical bowel preparation, early restoration of diet and early postoperative ambulation.
Sponsors
Quan Wang
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
No minimum to 75 Years
Healthy volunteers
No
Inclusion criteria
* Age ≤75 years * Good nutrition * no systemic infection * Elective laparoscopic surgery
Exclusion criteria
* Age \>75 years * Malnutrition or an organ system infection * Associated with obstruction, bleeding, emergency surgery or surgical intervention * Tumor with extensive metastasis * Before operation patient was fasting, underwent gastrointestinal decompression and received nutritional support * Previous history of abdominal surgery * Patient had previously undergone gastrostomy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| solid diet time | with the first 30 days(plus or minus 3days) after surgery |
| Postoperative days | with the first 30 days(plus or minus 3days) after surgery |
| First flatus time | with the first 30 days(plus or minus 3days) after surgery |
| First defecation time | with the first 30 days(plus or minus 3days) after surgery |
| Length of hospital stay | with the first 30 days(plus or minus 3days) after surgery |
Secondary
| Measure | Time frame |
|---|---|
| CRP (mg/L) | with the first 30 days(plus or minus 3days) after surgery |
| Complications:anastomotic leakage,intestinal obstruction,wound infection | one year |
| Analgesics | with the first 30 days(plus or minus 3days) after surgery |
Outcome results
None listed