In-vivo Efficacy Study of Patient Pre-operative Preps

Assessment of the Antimicrobial Efficacy of 3M CHG/IPA Preoperative Skin Preparation Against Resident Human Skin Flora on the Abdominal and Inguinal Regions

Status

Completed

Phases

Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01968707

Enrollment

426

Registered

2013-10-24

Start date

2013-10-31

Completion date

2014-06-30

Last updated

2024-10-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bacterial Reduction on Skin Flora Post-product Application

Keywords

surgical prep, CHG, IPA

Brief summary

The purpose of this study is to determine the antimicrobial efficacy of the 3M CHG/IPA Prep on skin flora of the abdominal and inguinal regions of human subjects.

Detailed description

The primary efficacy is evaluated by demonstration that the product provides a lower bound of the 95% confidence interval of percent responders that is greater than or equal to 70%. On the abdominal sites, a responder is defined as a subject with a 2-log10 per cm2 bacterial reduction at 10 minutes and for whom the skin flora does not return to baseline at 6 hours. On the inguinal sites, a responder is defined as a subject with a 3-log10 per cm2 bacterial reduction at 10 minutes and for whom the skin flora does not return to baseline at 6 hours.

Interventions

DRUGChloraPrep Hi-Lite Orange

Apply topically.

DRUGNormal saline

Apply topically.

DRUG3M CHG/IPA Prep Tint 10.5-mL

Apply topically.

DRUG3M CHG/IPA Prep Tint 26-mL

Apply topically

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* Subjects of any race * Subjects in good general health * Minimum skin flora baseline requirements on abdomen and groin

Exclusion criteria

* Any tattoos, scars, breaks in the skin, or any form of dermatitis, or other skin disorders (including acne) on the applicable test areas * Topical antimicrobial exposure within 14 days prior to screening and treatment days * Use of systemic or topical antibiotics, steroid medications, or any other products known to affect the normal microbial flora of the skin within 14 days prior to screening and treatment days

Design outcomes

Primary

Measure	Time frame	Description
Responder Rate	baseline, 10 minutes post-product application and 6 hour post-product application	On the abdominal region a responder was a subject with a 2 log10/cm2 bacterial reduction at 10 minutes and for whom the skin flora did not return to baseline. On the inguinal region a responder was a subject with a 3 log10/cm2 bacterial reduction at 10 minutes and for whom the skin flora did not return to baseline.

Secondary

Measure	Time frame	Description
Reduction of Skin Flora 10 Minutes Post-treatment	10 minutes	log10/cm2 reduction of skin flora, relative to treatment day baseline (log10/cm2), at 10 minutes post-treatment
Skin Flora Recovery 6-hours Post-treatment	6 hours post-treatment	Log10/cm2 recovery of skin flora at 6 hours following application of study treatment
Reduction of Skin Flora 6 Hours Post-treatment	6 hours	log10/cm2 reduction of skin flora, relative to treatment day baseline (log10/cm2), at 6 hours post-treatment
Skin Flora Baseline for the Abdominal and Inguinal Region.	Baseline	Log10/cm2 baseline skin flora for abdominal and inguinal regions
Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Assessed at baseline (pre-treatment) and 10 minute post-treatment and 6 hour post-treatment.	Skin irritation (dryness, edema, erythema, rash) assessed on the test sites using a 0-3 rating scale: 0=no reaction, 1=mild, 2=moderated, 3=severe
Skin Flora Recovery 10 Minutes Post-treatment	10 minutes post-treatment	Log10/cm2 recovery of skin flora at 10 minutes following application of study treatments

Countries

United States

Participant flow

Pre-assignment details

This is a randomized, paired comparison design where each subject received 2 of the planned treatments, 1 on the left side & 1 on the right. Each subject provided 2 abdomen test sites, left & right and/or 2 inguen test sites, left & right. 406 subjects were randomized for the abdomen region & 391 subjects randomized for the inguen region resulting in 426 subjects providing 1594 applications of test products on 2 anatomical regions.

Participants by arm

Arm	Count
ChloraPrep Hi-Lite Orange - Abdominal ChloraPrep 2% CHG/70% IPA 26-mL applicator applied topically for 30 seconds.	247
ChloraPrep Hi-Lite Orange - Abdominal ChloraPrep 2% CHG/70% IPA 26-mL applicator applied topically for 30 seconds.	247
Normal Saline - Abdominal Normal Saline with applicator applied topically for 30 seconds.	74
Normal Saline - Abdominal Normal Saline with applicator applied topically for 30 seconds.	74
3M CHG/IPA Prep Tint 10.5-mL - Abdominal 3M CHG/IPA 2% CHG/70% IPA 10.5-mL applicator applied topically for 30 seconds.	246
3M CHG/IPA Prep Tint 10.5-mL - Abdominal 3M CHG/IPA 2% CHG/70% IPA 10.5-mL applicator applied topically for 30 seconds.	246
3M CHG/IPA Prep Tint 26-mL - Abdominal 3M CHG/IPA 2% CHG/70% IPA 26-mL applicator applied topically for 30 seconds.	245
3M CHG/IPA Prep Tint 26-mL - Abdominal 3M CHG/IPA 2% CHG/70% IPA 26-mL applicator applied topically for 30 seconds.	245
ChloraPrep Hi-Lite Orange - Inguinal ChloraPrep 2% CHG/70% IPA 26-mL applicator applied topically for 2 minutes.	236
ChloraPrep Hi-Lite Orange - Inguinal ChloraPrep 2% CHG/70% IPA 26-mL applicator applied topically for 2 minutes.	236
Normal Saline - Inguinal Normal Saline with applicator applied topically for 2 minutes.	70
Normal Saline - Inguinal Normal Saline with applicator applied topically for 2 minutes.	70
3M CHG/IPA Prep Tint 10.5-mL - Inguinal 3M CHG/IPA 2% CHG/70% IPA 10.5-mL applicator applied topically for 2 minutes.	238
3M CHG/IPA Prep Tint 10.5-mL - Inguinal 3M CHG/IPA 2% CHG/70% IPA 10.5-mL applicator applied topically for 2 minutes.	238
3M CHG/IPA Prep 26-mL - Inguinal 3M CHG/IPA 2% CHG/70% IPA 26-mL applicator applied topically for 2 minutes.	238
3M CHG/IPA Prep 26-mL - Inguinal 3M CHG/IPA 2% CHG/70% IPA 26-mL applicator applied topically for 2 minutes.	238
Total	3,188

Withdrawals & dropouts

Period	Reason	FG000	FG001	FG002	FG003	FG004	FG005	FG006	FG007
Overall Study	Did not meet treatment day baseline	49	12	41	44	36	11	34	35

Baseline characteristics

Characteristic	Total	Normal Saline - Abdominal	3M CHG/IPA Prep Tint 10.5-mL - Abdominal	3M CHG/IPA Prep Tint 26-mL - Abdominal	ChloraPrep Hi-Lite Orange - Abdominal	ChloraPrep Hi-Lite Orange - Inguinal	Normal Saline - Inguinal	3M CHG/IPA Prep Tint 10.5-mL - Inguinal	3M CHG/IPA Prep 26-mL - Inguinal
Age, Customized <=18 years	0 participants	74 participants	246 participants	246 participants	247 participants	236 participants	70 participants	238 participants	238 participants
Age, Customized >=65 years	17 participants	74 participants	246 participants	245 participants	247 participants	236 participants	70 participants	238 participants	238 participants
Age, Customized Between 18 and 65 years	409 participants	74 participants	246 participants	246 participants	247 participants	236 participants	70 participants	238 participants	238 participants
Race/Ethnicity, Customized American Indian or Alaska Native	2 participants	74 participants	246 participants	245 participants	247 participants	236 participants	70 participants	238 participants	238 participants
Race/Ethnicity, Customized Asian	136 participants	74 participants	246 participants	245 participants	247 participants	236 participants	70 participants	238 participants	238 participants
Race/Ethnicity, Customized Black or African American	70 participants	74 participants	246 participants	245 participants	247 participants	236 participants	70 participants	238 participants	238 participants
Race/Ethnicity, Customized Hispanic/Latino	49 participants	74 participants	246 participants	245 participants	247 participants	236 participants	70 participants	238 participants	238 participants
Race/Ethnicity, Customized Native Hawiian or Other Pacific Islander	2 participants	74 participants	246 participants	245 participants	247 participants	236 participants	70 participants	238 participants	238 participants
Race/Ethnicity, Customized Other	7 participants	74 participants	246 participants	245 participants	247 participants	236 participants	70 participants	238 participants	238 participants
Race/Ethnicity, Customized White	160 participants	74 participants	246 participants	245 participants	247 participants	236 participants	70 participants	237 participants	238 participants
Region of Enrollment United States	426 participants	74 participants	246 participants	245 participants	247 participants	236 participants	70 participants	238 participants	238 participants
Sex/Gender, Customized Female	213 participants	74 participants	246 participants	245 participants	247 participants	236 participants	70 participants	238 participants	238 participants
Sex/Gender, Customized Male	213 participants	74 participants	246 participants	245 participants	247 participants	236 participants	70 participants	238 participants	238 participants

Adverse events

Event type	EG000 affected / at risk	EG001 affected / at risk	EG002 affected / at risk	EG003 affected / at risk	EG004 affected / at risk	EG005 affected / at risk	EG006 affected / at risk	EG007 affected / at risk
deaths Total, all-cause mortality	0 / 247	0 / 74	0 / 246	0 / 245	0 / 236	0 / 70	0 / 238	0 / 238
other Total, other adverse events	0 / 247	0 / 74	0 / 246	0 / 245	0 / 236	0 / 70	0 / 238	0 / 238
serious Total, serious adverse events	0 / 247	0 / 74	0 / 246	0 / 245	0 / 236	0 / 70	0 / 238	0 / 238

Outcome results

Primary

Responder Rate

On the abdominal region a responder was a subject with a 2 log10/cm2 bacterial reduction at 10 minutes and for whom the skin flora did not return to baseline. On the inguinal region a responder was a subject with a 3 log10/cm2 bacterial reduction at 10 minutes and for whom the skin flora did not return to baseline.

Time frame: baseline, 10 minutes post-product application and 6 hour post-product application

Population: The primary analysis data set used a Modified Intent to Treat population. Subjects were excluded who did not meet the treatment day baseline requirements of either \> or equal to 3.0 log10 on the abdomen test site or 5.0 log10 on the inguinal test site.

Arm	Measure	Value (COUNT_OF_PARTICIPANTS)
ChloraPrep Hi-Lite Orange - Abdominal	Responder Rate	178 Participants
3M CHG/IPA Prep Tint 10.5-mL - Abdominal	Responder Rate	167 Participants
3M CHG/IPA Prep Tint 26-mL - Abdominal	Responder Rate	175 Participants
Normal Saline - Abdominal	Responder Rate	0 Participants
ChloraPrep Hi-Lite Orange - Inguinal	Responder Rate	168 Participants
3M CHG/IPA Prep Tint 10.5-mL - Inguinal	Responder Rate	168 Participants
3M CHG/IPA Prep Tint 26-mL - Inguinal	Responder Rate	162 Participants
Normal Saline - Inguinal	Responder Rate	4 Participants

Secondary

Reduction of Skin Flora 10 Minutes Post-treatment

log10/cm2 reduction of skin flora, relative to treatment day baseline (log10/cm2), at 10 minutes post-treatment

Time frame: 10 minutes

Arm	Measure	Value (MEAN)	Dispersion
ChloraPrep Hi-Lite Orange - Abdominal	Reduction of Skin Flora 10 Minutes Post-treatment	2.79 log10/cm2	Standard Deviation 0.565
3M CHG/IPA Prep Tint 10.5-mL - Abdominal	Reduction of Skin Flora 10 Minutes Post-treatment	0.64 log10/cm2	Standard Deviation 0.488
3M CHG/IPA Prep Tint 26-mL - Abdominal	Reduction of Skin Flora 10 Minutes Post-treatment	2.66 log10/cm2	Standard Deviation 0.706
Normal Saline - Abdominal	Reduction of Skin Flora 10 Minutes Post-treatment	2.74 log10/cm2	Standard Deviation 0.644
ChloraPrep Hi-Lite Orange - Inguinal	Reduction of Skin Flora 10 Minutes Post-treatment	4.04 log10/cm2	Standard Deviation 0.964
3M CHG/IPA Prep Tint 10.5-mL - Inguinal	Reduction of Skin Flora 10 Minutes Post-treatment	1.34 log10/cm2	Standard Deviation 1.096
3M CHG/IPA Prep Tint 26-mL - Inguinal	Reduction of Skin Flora 10 Minutes Post-treatment	3.98 log10/cm2	Standard Deviation 1.034
Normal Saline - Inguinal	Reduction of Skin Flora 10 Minutes Post-treatment	3.89 log10/cm2	Standard Deviation 0.929

Secondary

Reduction of Skin Flora 6 Hours Post-treatment

log10/cm2 reduction of skin flora, relative to treatment day baseline (log10/cm2), at 6 hours post-treatment

Time frame: 6 hours

Arm	Measure	Value (MEAN)	Dispersion
ChloraPrep Hi-Lite Orange - Abdominal	Reduction of Skin Flora 6 Hours Post-treatment	1.77 log10/cm2	Standard Deviation 0.899
3M CHG/IPA Prep Tint 10.5-mL - Abdominal	Reduction of Skin Flora 6 Hours Post-treatment	0.47 log10/cm2	Standard Deviation 0.651
3M CHG/IPA Prep Tint 26-mL - Abdominal	Reduction of Skin Flora 6 Hours Post-treatment	1.48 log10/cm2	Standard Deviation 0.866
Normal Saline - Abdominal	Reduction of Skin Flora 6 Hours Post-treatment	1.64 log10/cm2	Standard Deviation 0.864
ChloraPrep Hi-Lite Orange - Inguinal	Reduction of Skin Flora 6 Hours Post-treatment	2.64 log10/cm2	Standard Deviation 1.047
3M CHG/IPA Prep Tint 10.5-mL - Inguinal	Reduction of Skin Flora 6 Hours Post-treatment	1.08 log10/cm2	Standard Deviation 0.833
3M CHG/IPA Prep Tint 26-mL - Inguinal	Reduction of Skin Flora 6 Hours Post-treatment	2.24 log10/cm2	Standard Deviation 1.103
Normal Saline - Inguinal	Reduction of Skin Flora 6 Hours Post-treatment	2.35 log10/cm2	Standard Deviation 1.045

Secondary

Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score

Skin irritation (dryness, edema, erythema, rash) assessed on the test sites using a 0-3 rating scale: 0=no reaction, 1=mild, 2=moderated, 3=severe

Time frame: Assessed at baseline (pre-treatment) and 10 minute post-treatment and 6 hour post-treatment.

Population: The primary safety analysis data set used an Intent to Treat population.

Arm	Measure	Group	Value (NUMBER)
ChloraPrep Hi-Lite Orange - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Rash-No Reaction (0)	247 test sites on skin
ChloraPrep Hi-Lite Orange - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Dryness-No Reaction (0)	247 test sites on skin
ChloraPrep Hi-Lite Orange - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Dryness-Moderate (2)	0 test sites on skin
ChloraPrep Hi-Lite Orange - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Dryness-Severe (3)	0 test sites on skin
ChloraPrep Hi-Lite Orange - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Edema-No Reaction (0)	247 test sites on skin
ChloraPrep Hi-Lite Orange - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Edema-Mild (1)	0 test sites on skin
ChloraPrep Hi-Lite Orange - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Edema-Moderate (2)	0 test sites on skin
ChloraPrep Hi-Lite Orange - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Edema-Severe (3)	0 test sites on skin
ChloraPrep Hi-Lite Orange - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Erythema-No Reaction (0)	247 test sites on skin
ChloraPrep Hi-Lite Orange - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Erythema-Mild (1)	0 test sites on skin
ChloraPrep Hi-Lite Orange - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Erythema-Moderate (2)	0 test sites on skin
ChloraPrep Hi-Lite Orange - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Erythema-Severe (3)	0 test sites on skin
ChloraPrep Hi-Lite Orange - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Dryness-Mild (1)	0 test sites on skin
ChloraPrep Hi-Lite Orange - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Rash-Mild (1)	0 test sites on skin
ChloraPrep Hi-Lite Orange - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Rash-Moderate (2)	0 test sites on skin
ChloraPrep Hi-Lite Orange - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Rash-Severe (3)	0 test sites on skin
ChloraPrep Hi-Lite Orange - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Dryness-No Reaction (0)	247 test sites on skin
ChloraPrep Hi-Lite Orange - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Dryness-Mild (1)	0 test sites on skin
ChloraPrep Hi-Lite Orange - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Dryness-Moderate (2)	0 test sites on skin
ChloraPrep Hi-Lite Orange - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Dryness-Severe (3)	0 test sites on skin
ChloraPrep Hi-Lite Orange - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Edema-No Reaction (0)	247 test sites on skin
ChloraPrep Hi-Lite Orange - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Edema-Mild (1)	0 test sites on skin
ChloraPrep Hi-Lite Orange - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Edema-Moderate (2)	0 test sites on skin
ChloraPrep Hi-Lite Orange - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Edema-Severe (3)	0 test sites on skin
ChloraPrep Hi-Lite Orange - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Erythema-No Reaction (0)	247 test sites on skin
ChloraPrep Hi-Lite Orange - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Erythema-Mild (1)	0 test sites on skin
ChloraPrep Hi-Lite Orange - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Erythema-Moderate (2)	0 test sites on skin
ChloraPrep Hi-Lite Orange - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Erythema-Severe (3)	0 test sites on skin
ChloraPrep Hi-Lite Orange - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Rash-No Reaction (0)	247 test sites on skin
ChloraPrep Hi-Lite Orange - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Rash-Mild (1)	0 test sites on skin
ChloraPrep Hi-Lite Orange - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Rash-Mild (2)	0 test sites on skin
ChloraPrep Hi-Lite Orange - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Rash-Severe (3)	0 test sites on skin
ChloraPrep Hi-Lite Orange - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Dryness-No Reaction (0)	247 test sites on skin
ChloraPrep Hi-Lite Orange - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Dryness-Mild (1)	0 test sites on skin
ChloraPrep Hi-Lite Orange - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Dryness-Moderate (2)	0 test sites on skin
ChloraPrep Hi-Lite Orange - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Dryness-Severe (3)	0 test sites on skin
ChloraPrep Hi-Lite Orange - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Edema-No Reaction (0)	247 test sites on skin
ChloraPrep Hi-Lite Orange - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Edema-Mild (1)	0 test sites on skin
ChloraPrep Hi-Lite Orange - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Edema-Moderate (2)	0 test sites on skin
ChloraPrep Hi-Lite Orange - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Edema-Severe (3)	0 test sites on skin
ChloraPrep Hi-Lite Orange - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Erythema-No Reaction (0)	247 test sites on skin
ChloraPrep Hi-Lite Orange - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Erythema-Mild (1)	0 test sites on skin
ChloraPrep Hi-Lite Orange - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Erythema-Moderate (2)	0 test sites on skin
ChloraPrep Hi-Lite Orange - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Erythema-Severe (3)	0 test sites on skin
ChloraPrep Hi-Lite Orange - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Rash-No Reaction (0)	247 test sites on skin
ChloraPrep Hi-Lite Orange - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Rash-Mild (1)	0 test sites on skin
ChloraPrep Hi-Lite Orange - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Rash-Moderate (2)	0 test sites on skin
ChloraPrep Hi-Lite Orange - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Rash-Severe (3)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Rash-Severe (3)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Dryness-Moderate (2)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Erythema-No Reaction (0)	74 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Edema-Severe (3)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Edema-Moderate (2)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Dryness-Severe (3)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Erythema-No Reaction (0)	74 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Edema-Moderate (2)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Edema-Mild (1)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Edema-No Reaction (0)	74 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Dryness-No Reaction (0)	74 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Erythema-Moderate (2)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Erythema-Severe (3)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Erythema-Mild (1)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Edema-Mild (1)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Dryness-Mild (1)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Erythema-Mild (1)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Erythema-Moderate (2)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Rash-Severe (3)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Erythema-No Reaction (0)	74 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Edema-No Reaction (0)	74 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Erythema-Severe (3)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Edema-Severe (3)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Edema-Moderate (2)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Edema-Mild (1)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Rash-No Reaction (0)	74 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Edema-Severe (3)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Edema-No Reaction (0)	74 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Dryness-Severe (3)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Rash-Mild (1)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Dryness-Moderate (2)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Dryness-Mild (1)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Rash-Moderate (2)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Rash-Moderate (2)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Dryness-No Reaction (0)	74 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Rash-Severe (3)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Dryness-Severe (3)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Rash-Mild (2)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Rash-Mild (1)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Rash-No Reaction (0)	74 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Dryness-No Reaction (0)	74 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Erythema-Severe (3)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Erythema-Moderate (2)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Rash-No Reaction (0)	74 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Dryness-Mild (1)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Dryness-Moderate (2)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Erythema-Mild (1)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Rash-Mild (1)	0 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Rash-Mild (2)	0 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Dryness-Moderate (2)	0 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Dryness-Moderate (2)	0 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Erythema-Moderate (2)	0 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Erythema-No Reaction (0)	246 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Rash-No Reaction (0)	246 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Edema-Severe (3)	0 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Rash-Severe (3)	0 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Edema-No Reaction (0)	246 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Erythema-Severe (3)	0 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Dryness-Severe (3)	0 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Dryness-Severe (3)	0 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Edema-Moderate (2)	0 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Rash-Mild (1)	0 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Edema-Mild (1)	0 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Dryness-Moderate (2)	0 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Edema-No Reaction (0)	246 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Rash-Mild (1)	0 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Erythema-No Reaction (0)	246 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Edema-Mild (1)	0 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Dryness-No Reaction (0)	246 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Rash-Mild (1)	0 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Edema-Severe (3)	0 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Dryness-Mild (1)	0 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Erythema-Moderate (2)	0 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Rash-Moderate (2)	0 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Erythema-Mild (1)	0 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Dryness-Mild (1)	0 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Rash-No Reaction (0)	246 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Rash-Severe (3)	0 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Erythema-Mild (1)	0 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Dryness-Mild (1)	0 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Erythema-Severe (3)	0 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Erythema-Mild (1)	0 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Erythema-Moderate (2)	0 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Edema-No Reaction (0)	246 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Rash-Moderate (2)	0 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Erythema-No Reaction (0)	246 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Edema-Moderate (2)	0 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Edema-Severe (3)	0 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Dryness-No Reaction (0)	246 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Dryness-No Reaction (0)	246 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Erythema-Severe (3)	0 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Dryness-Severe (3)	0 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Rash-Severe (3)	0 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Edema-Moderate (2)	0 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Rash-No Reaction (0)	246 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Edema-Mild (1)	0 test sites on skin
Normal Saline - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Edema-Mild (1)	0 test sites on skin
Normal Saline - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Edema-Moderate (2)	0 test sites on skin
Normal Saline - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Edema-Severe (3)	0 test sites on skin
Normal Saline - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Rash-Severe (3)	0 test sites on skin
Normal Saline - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Erythema-No Reaction (0)	245 test sites on skin
Normal Saline - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Erythema-Mild (1)	0 test sites on skin
Normal Saline - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Erythema-Moderate (2)	0 test sites on skin
Normal Saline - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Erythema-Severe (3)	0 test sites on skin
Normal Saline - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Erythema-Severe (3)	0 test sites on skin
Normal Saline - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Rash-No Reaction (0)	245 test sites on skin
Normal Saline - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Rash-Mild (1)	0 test sites on skin
Normal Saline - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Rash-Moderate (2)	0 test sites on skin
Normal Saline - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Rash-Severe (3)	0 test sites on skin
Normal Saline - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Dryness-No Reaction (0)	245 test sites on skin
Normal Saline - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Dryness-Mild (1)	0 test sites on skin
Normal Saline - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Dryness-Moderate (2)	0 test sites on skin
Normal Saline - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Rash-No Reaction (0)	245 test sites on skin
Normal Saline - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Dryness-Severe (3)	0 test sites on skin
Normal Saline - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Edema-No Reaction (0)	245 test sites on skin
Normal Saline - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Edema-Mild (1)	0 test sites on skin
Normal Saline - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Edema-Moderate (2)	0 test sites on skin
Normal Saline - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Edema-Severe (3)	0 test sites on skin
Normal Saline - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Erythema-No Reaction (0)	245 test sites on skin
Normal Saline - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Erythema-Mild (1)	0 test sites on skin
Normal Saline - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Erythema-Moderate (2)	0 test sites on skin
Normal Saline - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Rash-Mild (1)	0 test sites on skin
Normal Saline - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Erythema-Severe (3)	0 test sites on skin
Normal Saline - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Rash-No Reaction (0)	245 test sites on skin
Normal Saline - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Rash-Mild (1)	0 test sites on skin
Normal Saline - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Rash-Mild (2)	0 test sites on skin
Normal Saline - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Rash-Severe (3)	0 test sites on skin
Normal Saline - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Dryness-No Reaction (0)	245 test sites on skin
Normal Saline - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Dryness-Mild (1)	0 test sites on skin
Normal Saline - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Dryness-Moderate (2)	0 test sites on skin
Normal Saline - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Rash-Moderate (2)	0 test sites on skin
Normal Saline - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Dryness-Severe (3)	0 test sites on skin
Normal Saline - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Edema-No Reaction (0)	245 test sites on skin
Normal Saline - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Edema-Moderate (2)	0 test sites on skin
Normal Saline - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Edema-Severe (3)	0 test sites on skin
Normal Saline - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Erythema-No Reaction (0)	245 test sites on skin
Normal Saline - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Erythema-Mild (1)	0 test sites on skin
Normal Saline - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Dryness-No Reaction (0)	245 test sites on skin
Normal Saline - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Dryness-Mild (1)	0 test sites on skin
Normal Saline - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Dryness-Moderate (2)	0 test sites on skin
Normal Saline - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Erythema-Moderate (2)	0 test sites on skin
Normal Saline - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Dryness-Severe (3)	0 test sites on skin
Normal Saline - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Edema-No Reaction (0)	245 test sites on skin
Normal Saline - Abdominal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Edema-Mild (1)	0 test sites on skin
ChloraPrep Hi-Lite Orange - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Edema-Moderate (2)	0 test sites on skin
ChloraPrep Hi-Lite Orange - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Rash-No Reaction (0)	236 test sites on skin
ChloraPrep Hi-Lite Orange - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Edema-No Reaction (0)	236 test sites on skin
ChloraPrep Hi-Lite Orange - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Edema-No Reaction (0)	236 test sites on skin
ChloraPrep Hi-Lite Orange - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Erythema-Severe (3)	0 test sites on skin
ChloraPrep Hi-Lite Orange - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Dryness-No Reaction (0)	236 test sites on skin
ChloraPrep Hi-Lite Orange - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Edema-Mild (1)	0 test sites on skin
ChloraPrep Hi-Lite Orange - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Dryness-Severe (3)	0 test sites on skin
ChloraPrep Hi-Lite Orange - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Erythema-Mild (1)	0 test sites on skin
ChloraPrep Hi-Lite Orange - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Erythema-Severe (3)	0 test sites on skin
ChloraPrep Hi-Lite Orange - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Edema-Moderate (2)	0 test sites on skin
ChloraPrep Hi-Lite Orange - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Erythema-Moderate (2)	0 test sites on skin
ChloraPrep Hi-Lite Orange - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Erythema-Severe (3)	0 test sites on skin
ChloraPrep Hi-Lite Orange - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Edema-Severe (3)	0 test sites on skin
ChloraPrep Hi-Lite Orange - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Rash-Mild (1)	0 test sites on skin
ChloraPrep Hi-Lite Orange - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Erythema-No Reaction (0)	236 test sites on skin
ChloraPrep Hi-Lite Orange - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Rash-Severe (3)	0 test sites on skin
ChloraPrep Hi-Lite Orange - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Rash-No Reaction (0)	236 test sites on skin
ChloraPrep Hi-Lite Orange - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Edema-Severe (3)	0 test sites on skin
ChloraPrep Hi-Lite Orange - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Edema-Mild (1)	0 test sites on skin
ChloraPrep Hi-Lite Orange - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Dryness-Severe (3)	0 test sites on skin
ChloraPrep Hi-Lite Orange - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Rash-Mild (1)	0 test sites on skin
ChloraPrep Hi-Lite Orange - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Rash-Severe (3)	0 test sites on skin
ChloraPrep Hi-Lite Orange - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Rash-Mild (2)	0 test sites on skin
ChloraPrep Hi-Lite Orange - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Erythema-Mild (1)	0 test sites on skin
ChloraPrep Hi-Lite Orange - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Edema-No Reaction (0)	236 test sites on skin
ChloraPrep Hi-Lite Orange - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Rash-No Reaction (0)	236 test sites on skin
ChloraPrep Hi-Lite Orange - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Erythema-No Reaction (0)	236 test sites on skin
ChloraPrep Hi-Lite Orange - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Rash-Severe (3)	0 test sites on skin
ChloraPrep Hi-Lite Orange - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Dryness-Mild (1)	0 test sites on skin
ChloraPrep Hi-Lite Orange - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Rash-Moderate (2)	0 test sites on skin
ChloraPrep Hi-Lite Orange - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Dryness-Mild (1)	0 test sites on skin
ChloraPrep Hi-Lite Orange - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Dryness-No Reaction (0)	236 test sites on skin
ChloraPrep Hi-Lite Orange - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Edema-Moderate (2)	0 test sites on skin
ChloraPrep Hi-Lite Orange - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Rash-Moderate (2)	0 test sites on skin
ChloraPrep Hi-Lite Orange - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Erythema-Moderate (2)	0 test sites on skin
ChloraPrep Hi-Lite Orange - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Dryness-Mild (1)	0 test sites on skin
ChloraPrep Hi-Lite Orange - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Edema-Mild (1)	0 test sites on skin
ChloraPrep Hi-Lite Orange - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Dryness-No Reaction (0)	236 test sites on skin
ChloraPrep Hi-Lite Orange - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Rash-Mild (1)	0 test sites on skin
ChloraPrep Hi-Lite Orange - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Dryness-Moderate (2)	0 test sites on skin
ChloraPrep Hi-Lite Orange - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Erythema-Moderate (2)	0 test sites on skin
ChloraPrep Hi-Lite Orange - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Erythema-No Reaction (0)	236 test sites on skin
ChloraPrep Hi-Lite Orange - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Dryness-Moderate (2)	0 test sites on skin
ChloraPrep Hi-Lite Orange - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Dryness-Moderate (2)	0 test sites on skin
ChloraPrep Hi-Lite Orange - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Dryness-Severe (3)	0 test sites on skin
ChloraPrep Hi-Lite Orange - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Edema-Severe (3)	0 test sites on skin
ChloraPrep Hi-Lite Orange - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Erythema-Mild (1)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Dryness-Moderate (2)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Rash-No Reaction (0)	70 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Dryness-Severe (3)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Edema-No Reaction (0)	70 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Dryness-Severe (3)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Edema-No Reaction (0)	70 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Dryness-No Reaction (0)	70 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Erythema-Mild (1)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Rash-Moderate (2)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Erythema-Severe (3)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Erythema-Mild (1)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Rash-Mild (2)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Rash-Severe (3)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Edema-Mild (1)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Dryness-No Reaction (0)	70 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Edema-Severe (3)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Erythema-No Reaction (0)	70 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Erythema-Severe (3)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Erythema-Severe (3)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Edema-No Reaction (0)	70 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Erythema-Mild (1)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Edema-Moderate (2)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Edema-Severe (3)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Erythema-Moderate (2)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Edema-Moderate (2)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Erythema-Moderate (2)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Erythema-No Reaction (0)	70 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Dryness-Severe (3)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Rash-Severe (3)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Edema-Severe (3)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Edema-Moderate (2)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Dryness-Mild (1)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Erythema-Moderate (2)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Dryness-Mild (1)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Edema-Mild (1)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Edema-Mild (1)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Rash-Moderate (2)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Rash-No Reaction (0)	70 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Dryness-Moderate (2)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Erythema-No Reaction (0)	70 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Rash-Mild (1)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Dryness-Moderate (2)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Rash-Severe (3)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Rash-Mild (1)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Dryness-No Reaction (0)	70 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Rash-Mild (1)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Dryness-Mild (1)	0 test sites on skin
3M CHG/IPA Prep Tint 10.5-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Rash-No Reaction (0)	70 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Erythema-Severe (3)	0 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Dryness-Moderate (2)	0 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Erythema-No Reaction (0)	238 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Dryness-Mild (1)	0 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Erythema-Mild (1)	0 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Dryness-No Reaction (0)	238 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Erythema-Moderate (2)	0 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Erythema-Severe (3)	0 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Rash-No Reaction (0)	238 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Rash-Severe (3)	0 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Rash-Mild (1)	0 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Rash-Mild (1)	0 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Rash-Mild (2)	0 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Rash-Moderate (2)	0 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Dryness-Severe (3)	0 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Rash-Severe (3)	0 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Rash-Severe (3)	0 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Dryness-No Reaction (0)	238 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Rash-Mild (1)	0 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Dryness-Mild (1)	0 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Dryness-Moderate (2)	0 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Edema-Moderate (2)	0 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Rash-No Reaction (0)	238 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Edema-Mild (1)	0 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Dryness-Severe (3)	0 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Edema-No Reaction (0)	238 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Erythema-Moderate (2)	0 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Edema-Mild (1)	0 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Rash-Moderate (2)	0 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Erythema-Severe (3)	0 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Edema-Moderate (2)	0 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Edema-No Reaction (0)	238 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Edema-Severe (3)	0 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Erythema-Moderate (2)	0 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Erythema-No Reaction (0)	238 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Erythema-Mild (1)	0 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Erythema-Mild (1)	0 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Erythema-No Reaction (0)	238 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Dryness-No Reaction (0)	238 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Dryness-Mild (1)	0 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Edema-Severe (3)	0 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Edema-No Reaction (0)	238 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Dryness-Severe (3)	0 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Edema-Mild (1)	0 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Rash-No Reaction (0)	238 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Edema-Moderate (2)	0 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Dryness-Moderate (2)	0 test sites on skin
3M CHG/IPA Prep Tint 26-mL - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Edema-Severe (3)	0 test sites on skin
Normal Saline - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Edema-No Reaction (0)	238 test sites on skin
Normal Saline - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Dryness-Severe (3)	0 test sites on skin
Normal Saline - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Erythema-No Reaction (0)	238 test sites on skin
Normal Saline - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Erythema-Mild (1)	0 test sites on skin
Normal Saline - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Rash-No Reaction (0)	238 test sites on skin
Normal Saline - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Dryness-Moderate (2)	0 test sites on skin
Normal Saline - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Edema-Moderate (2)	0 test sites on skin
Normal Saline - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Dryness-Mild (1)	0 test sites on skin
Normal Saline - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Rash-Mild (1)	0 test sites on skin
Normal Saline - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Erythema-No Reaction (0)	238 test sites on skin
Normal Saline - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Dryness-No Reaction (0)	238 test sites on skin
Normal Saline - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Dryness-No Reaction (0)	238 test sites on skin
Normal Saline - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Dryness-Severe (3)	0 test sites on skin
Normal Saline - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Rash-Severe (3)	0 test sites on skin
Normal Saline - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Edema-Moderate (2)	0 test sites on skin
Normal Saline - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Dryness-Mild (1)	0 test sites on skin
Normal Saline - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Edema-Severe (3)	0 test sites on skin
Normal Saline - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Rash-No Reaction (0)	238 test sites on skin
Normal Saline - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Rash-Moderate (2)	0 test sites on skin
Normal Saline - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Rash-Mild (1)	0 test sites on skin
Normal Saline - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Rash-Mild (2)	0 test sites on skin
Normal Saline - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Erythema-Severe (3)	0 test sites on skin
Normal Saline - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Dryness-Moderate (2)	0 test sites on skin
Normal Saline - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Edema-No Reaction (0)	238 test sites on skin
Normal Saline - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Rash-Mild (1)	0 test sites on skin
Normal Saline - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Dryness-Severe (3)	0 test sites on skin
Normal Saline - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Edema-Severe (3)	0 test sites on skin
Normal Saline - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Edema-Mild (1)	0 test sites on skin
Normal Saline - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Rash-No Reaction (0)	238 test sites on skin
Normal Saline - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Rash-Severe (3)	0 test sites on skin
Normal Saline - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Dryness-Moderate (2)	0 test sites on skin
Normal Saline - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Edema-Mild (1)	0 test sites on skin
Normal Saline - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Dryness-Mild (1)	0 test sites on skin
Normal Saline - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Erythema-Severe (3)	0 test sites on skin
Normal Saline - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Rash-Severe (3)	0 test sites on skin
Normal Saline - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Edema-No Reaction (0)	238 test sites on skin
Normal Saline - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Edema-Severe (3)	0 test sites on skin
Normal Saline - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Erythema-Moderate (2)	0 test sites on skin
Normal Saline - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Erythema-Moderate (2)	0 test sites on skin
Normal Saline - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Erythema-No Reaction (0)	238 test sites on skin
Normal Saline - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Rash-Moderate (2)	0 test sites on skin
Normal Saline - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Erythema-Mild (1)	0 test sites on skin
Normal Saline - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Erythema-Moderate (2)	0 test sites on skin
Normal Saline - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Edema-Moderate (2)	0 test sites on skin
Normal Saline - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Edema-Mild (1)	0 test sites on skin
Normal Saline - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	Baseline Erythema-Severe (3)	0 test sites on skin
Normal Saline - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	10 minute Dryness-No Reaction (0)	238 test sites on skin
Normal Saline - Inguinal	Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score	6 hour Erythema-Mild (1)	0 test sites on skin

Secondary

Skin Flora Baseline for the Abdominal and Inguinal Region.

Log10/cm2 baseline skin flora for abdominal and inguinal regions

Time frame: Baseline

Arm	Measure	Value (MEAN)	Dispersion
ChloraPrep Hi-Lite Orange - Abdominal	Skin Flora Baseline for the Abdominal and Inguinal Region.	3.31 log10/cm2 skin flora	Standard Deviation 0.391
3M CHG/IPA Prep Tint 10.5-mL - Abdominal	Skin Flora Baseline for the Abdominal and Inguinal Region.	3.27 log10/cm2 skin flora	Standard Deviation 0.342
3M CHG/IPA Prep Tint 26-mL - Abdominal	Skin Flora Baseline for the Abdominal and Inguinal Region.	3.35 log10/cm2 skin flora	Standard Deviation 0.427
Normal Saline - Abdominal	Skin Flora Baseline for the Abdominal and Inguinal Region.	3.31 log10/cm2 skin flora	Standard Deviation 0.37
ChloraPrep Hi-Lite Orange - Inguinal	Skin Flora Baseline for the Abdominal and Inguinal Region.	5.44 log10/cm2 skin flora	Standard Deviation 0.479
3M CHG/IPA Prep Tint 10.5-mL - Inguinal	Skin Flora Baseline for the Abdominal and Inguinal Region.	5.40 log10/cm2 skin flora	Standard Deviation 0.448
3M CHG/IPA Prep Tint 26-mL - Inguinal	Skin Flora Baseline for the Abdominal and Inguinal Region.	5.44 log10/cm2 skin flora	Standard Deviation 0.49
Normal Saline - Inguinal	Skin Flora Baseline for the Abdominal and Inguinal Region.	5.42 log10/cm2 skin flora	Standard Deviation 0.469

Secondary

Skin Flora Recovery 10 Minutes Post-treatment

Log10/cm2 recovery of skin flora at 10 minutes following application of study treatments

Time frame: 10 minutes post-treatment

Arm	Measure	Value (MEAN)	Dispersion
ChloraPrep Hi-Lite Orange - Abdominal	Skin Flora Recovery 10 Minutes Post-treatment	0.52 log10/cm2 skin flora	Standard Deviation 0.5
3M CHG/IPA Prep Tint 10.5-mL - Abdominal	Skin Flora Recovery 10 Minutes Post-treatment	2.63 log10/cm2 skin flora	Standard Deviation 0.582
3M CHG/IPA Prep Tint 26-mL - Abdominal	Skin Flora Recovery 10 Minutes Post-treatment	0.69 log10/cm2 skin flora	Standard Deviation 0.604
Normal Saline - Abdominal	Skin Flora Recovery 10 Minutes Post-treatment	0.57 log10/cm2 skin flora	Standard Deviation 0.575
ChloraPrep Hi-Lite Orange - Inguinal	Skin Flora Recovery 10 Minutes Post-treatment	1.41 log10/cm2 skin flora	Standard Deviation 1.089
3M CHG/IPA Prep Tint 10.5-mL - Inguinal	Skin Flora Recovery 10 Minutes Post-treatment	4.06 log10/cm2 skin flora	Standard Deviation 1.211
3M CHG/IPA Prep Tint 26-mL - Inguinal	Skin Flora Recovery 10 Minutes Post-treatment	1.47 log10/cm2 skin flora	Standard Deviation 1.12
Normal Saline - Inguinal	Skin Flora Recovery 10 Minutes Post-treatment	1.53 log10/cm2 skin flora	Standard Deviation 1.039

Secondary

Skin Flora Recovery 6-hours Post-treatment

Log10/cm2 recovery of skin flora at 6 hours following application of study treatment

Time frame: 6 hours post-treatment

Arm	Measure	Value (MEAN)	Dispersion
ChloraPrep Hi-Lite Orange - Abdominal	Skin Flora Recovery 6-hours Post-treatment	1.54 log10/cm2 skin flora	Standard Deviation 0.808
3M CHG/IPA Prep Tint 10.5-mL - Abdominal	Skin Flora Recovery 6-hours Post-treatment	2.80 log10/cm2 skin flora	Standard Deviation 0.726
3M CHG/IPA Prep Tint 26-mL - Abdominal	Skin Flora Recovery 6-hours Post-treatment	1.87 log10/cm2 skin flora	Standard Deviation 0.804
Normal Saline - Abdominal	Skin Flora Recovery 6-hours Post-treatment	1.66 log10/cm2 skin flora	Standard Deviation 0.803
ChloraPrep Hi-Lite Orange - Inguinal	Skin Flora Recovery 6-hours Post-treatment	2.81 log10/cm2 skin flora	Standard Deviation 1.008
3M CHG/IPA Prep Tint 10.5-mL - Inguinal	Skin Flora Recovery 6-hours Post-treatment	4.31 log10/cm2 skin flora	Standard Deviation 0.941
3M CHG/IPA Prep Tint 26-mL - Inguinal	Skin Flora Recovery 6-hours Post-treatment	3.20 log10/cm2 skin flora	Standard Deviation 1.037
Normal Saline - Inguinal	Skin Flora Recovery 6-hours Post-treatment	3.07 log10/cm2 skin flora	Standard Deviation 1.032

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026

In-vivo Efficacy Study of Patient Pre-operative Preps

Conditions

Keywords

Brief summary

Detailed description

Related papers

Interventions

Sponsors

Study design

Eligibility

Inclusion criteria

Exclusion criteria

Design outcomes

Primary

Secondary

Countries

Participant flow

Pre-assignment details

Participants by arm

Withdrawals & dropouts

Baseline characteristics

Adverse events

Outcome results

Responder Rate

Reduction of Skin Flora 10 Minutes Post-treatment

Reduction of Skin Flora 6 Hours Post-treatment

Safety as Assessed by Skin Irritation (Dryness, Edema, Erythema, Rash) Rating Score

Skin Flora Baseline for the Abdominal and Inguinal Region.

Skin Flora Recovery 10 Minutes Post-treatment

Skin Flora Recovery 6-hours Post-treatment