Comfort and Tolerance of Surface Neuro Muscular Electrical Stimulation in Parkinson's Disease.

An Evaluation of Comfort and Tolerance of Surface Neuro Muscular Electrical Stimulation (NMES), When Applied to Parkinson's Disease Patients for Both Sensory and Motor Activation.

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01968473

Enrollment

Registered

2013-10-24

Start date

2013-09-30

Completion date

2013-10-31

Last updated

2013-10-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Parkinson's Disease

Keywords

Parkinson's disease, Freezing of Gait, Neuromuscular Electrical Stimulation, Comfort, Pain tolerance, Pain, Sensory threshold, Motor threshold, Pain threshold

Brief summary

The purpose of this study is to investigate issues relating to comfort and tolerance to surface neuro muscular electrical stimulation in a parkinson disease population.

Detailed description

The comfort and tolerance of Parkinson Disease (PD) patients to surface neuro muscular electrical stimulation (NMES) will be investigated. Six muscle sites will be tested sensory, motor and pain thresholds recorded. Furthermore pain tolerance will be recorded as the level at which the stimulus is unbearable.

Interventions

DEVICENMES Device comfort

NMES device, establishing Sensory, Motor and Pain thresholds and Pain tolerance.

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

SUPPORTIVE_CARE

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

ALL

Age

40 Years to 85 Years

Healthy volunteers

Inclusion criteria

* A diagnosis of idiopathic PD (UK, PD Brain Bank Criteria) * A Hoehn and Yahr stage of 2 - 4 * Exhibiting Freezing of Gait or another gait abnormalityin the ON or OFF state. * An ability to mobilise independently for the purpose of research when in the 'off' state * An ability to walk unaided for 10 meters.

Exclusion criteria

* A serious cognitive impairment (MMSE\<24) * Pregnant or currently involved in another clinical trial. * Uncontrolled heart problems * Pacemakers * On opioid or neuropathic pain medication

Design outcomes

Primary

Measure	Time frame	Description
Patient comfort in response to neuromuscular electrical stimulation in Parkinson's disease.	1 day	Participants will be tested over a range of stimulation intensities at different muscle sites. Primary outcome measure will be patient comfort and tolerance to neuromuscular electrical stimulation.

Countries

Ireland

Contacts

Primary ContactTimothy Counihan, MD, FRCPI

timothy.counihan@hse.ie0035391544251

Backup ContactPatrick Browne, RGN, MHSc

patrick.browne@hse.ie0035391893833

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026