Premature Infant
Conditions
Keywords
Very low birth weight infants, premature, nutrition, gastric residual
Brief summary
Omitting evaluation of gastric residual contents prior to feeding very premature infants will increase the feeding intake at 2 weeks, and total caloric intake and growth by 3 weeks, as well as decrease the time required for parenteral nutrition.
Detailed description
Infants were randomized into 2 groups. Group 1 had no gastric residuals evaluated prior to feeding. Group 2 had gastric residuals evaluated prior to feeding. Nutritional outcomes were compared between groups.
Interventions
OTHERNo gastric residual evaluation
Infants will not receive routine gastric residual evaluation prior to feeding.
Sponsors
The Gerber Foundation
University of Florida
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
No minimum to 3 Days
Healthy volunteers
No
Inclusion criteria
* Gestational age less than 32 weeks, * Birth weight less than or equal to 1250 grams, * Initial feeding tolerated within 48 hours of life
Exclusion criteria
* Congenital or chromosomal disorders, * Severe complications leading to death in the first week of life
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Amount of feeding intake at 2 weeks | Baseline to 2 weeks |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Days of parenteral nutrition | Baseline to approximately 21 days | — |
| Incidence of late onset sepsis | Baseline to approximately 90 days | — |
| Weekly or biweekly liver function tests | Baseline to 42 days | Direct bilirubin |
| Days to 120 mL/kg/d of enteral feedings | Baseline to approximately 21 days | — |
| Length of hospital stay | Baseline to approximately 90 days | — |
| Incidence of necrotizing enterocolitis | Baseline to approximately 90 days | — |
| Days requiring a central venous line | Baseline to approximately 21 days | — |
| Growth indices | Baseline to approximately 90 days | Weight, length and head circumference |
Countries
United States
Outcome results
None listed