Early Oral Feeding After Total Gastrectomy for Cancer

A Randomized Clinical Trial of Early Oral Feeding as a Component of Accelerated Recovery Protocol After Total Gastrectomy for Cancer

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01962519

Enrollment

112

Registered

2013-10-14

Start date

2012-01-31

Completion date

2014-12-31

Last updated

2013-10-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Adenocarcinoma of the Stomach

Keywords

gastrectomy, gastric cancer, oral feeding, complications

Brief summary

The aim of this study is to evaluate the possibility of shortening postoperative hospital stay after gastrectomy by early oral feeding as a component of an enhanced recovery protocol (ERAS).

Interventions

DIETARY_SUPPLEMENTEarly oral feeding

Oral fluids starting on POD 1, followed by a soft diet (thin purée six times a day) on day 2, and regular solid diet thereafter

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Inclusion criteria

* Total gastrectomy for cancer * Age 18 - 80 years * Informed consent

Exclusion criteria

* Numerous hepatic and peritoneal metastases * Extended resections (pancreas, colon) * Preoperative malnutrition requiring total parenteral nutrition * Emergency surgery

Design outcomes

Primary

Measure	Time frame	Description
Postoperative hospital stay	Participants will be followed for the duration of hospital stay, an expected average of 8 days	Time between surgery and patient discharge

Secondary

Measure	Time frame	Description
Morbidity	Participants will be followed for the duration of hospital stay, an expected average of 8 days	Any complication occurring during hospital stay

Other

Measure	Time frame	Description
Re-admissions	30 days after discharge	Hospital readmissions within 30 days after discharge
Effective oral feeding	Participants will be followed for the duration of hospital stay, an expected average of 8 days	Time to reach oral feeding covering 75% of patient's requirements
Quality of life	Preoperatively, postoperative day 7, 14 days after discharge	Quality of life measured by EORTC QLQ-C30 and EORTC QLQ - STO22
Laboratory parameters	Preoperatively, postoperative day 1 and 8	Laboratory tests, including lymphocyte count, blood albumin, blood prealbumin

Countries

Poland

Contacts

Primary ContactMarek Sierzega, MD, PhD

marek.sierzega@uj.edu.pl+48 124248007

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026