Frontotemporal Lobar Degeneration, Aging
Conditions
Brief summary
The purpose of this study is to examine the age and the neurodegenerative disease effects on social cognition. Secondary goals are to better understand the relationships between different component of social cognition, executive functioning, and behavior and describing the neuronal substrates associated to the alteration of the social cognition in ageing and dementia.
Interventions
BEHAVIORALCognitive assessment
Sponsors
Institut National de la Santé Et de la Recherche Médicale, France
University Hospital, Caen
Study design
Allocation
NON_RANDOMIZED
Intervention model
FACTORIAL
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
40 Years to 80 Years
Healthy volunteers
Yes
Inclusion criteria
* All the participants * Age between 40 and 80 years * Minimum of 7 years of education * French native speaker * Healthy subjects * Non pathological Dementia rating scale score * Patients * Clinical diagnosis of frontotemporal lobar degeneration
Exclusion criteria
* Chronic neurological disease * Encephalitis * Endocrinal disease * Hepatic disease * Case history of head injury with loss of consciousness of more than one hour * Case history of stroke * Case history of cancer during the five last years except squamous cell carcinomas * Alcoholism or drug addiction * Major psychiatric disorders according the Diagnostic and Statistical Manual of Mental Disorders
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Social cognition scores | 2 years | number of correct responses in a social cognition test |
Countries
France
Contacts
Primary ContactJulien Chavant
Outcome results
None listed