A Combined Training Program for Veterans With Amnestic Mild Cognitive Impairment

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01962038

Enrollment

Registered

2013-10-14

Start date

2013-05-31

Completion date

2017-11-30

Last updated

2018-04-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Amnestic Mild Cognitive Impairment

Keywords

Mild Cognitive Impairment, Aging

Brief summary

The purpose of this study is examine the efficacy of a combination physical exercise and cognitive training program on improving memory in older Veterans with amnestic Mild Cognitive Impairment.

Interventions

BEHAVIORALCombined Aerobic and Resistance Exercise

Gym and home based aerobic and resistance exercises

BEHAVIORALStretching Exercises

Gym and home based stretching exercises

BEHAVIORALCognitive Training

Group-based cognitive training

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

50 Years to 90 Years

Healthy volunteers

Inclusion criteria

* diagnosis of amnestic Mild Cognitive Impairment * available informant * visual and auditory acuity to allow neuropsychological testing * willingness to participate in exercise training + cognitive training for 8 months * approval of primary provider to participate in exercise trial

Exclusion criteria

* current severe psychiatric disorder * diagnosis of dementia * history of neurological or system illness affecting CNS function * acute illness or unstable chronic illness * current severe cardiac disease * inability to exercise consistently because of orthopedic or musculoskeletal problems * morbid obesity * inability to read, verbalize understanding and voluntarily sign the informed consent

Design outcomes

Primary

Measure	Time frame
Change from Baseline to 28 weeks in delayed recall of a word list	Baseline, 24 weeks, 28 weeks
Change from Baseline to 28 weeks in Delayed Recall of Names-Face Task	Baseline, 24 weeks, 28 weeks

Secondary

Measure	Time frame
Non-Cognitive Outcomes (Depression, Sleep, Quality of Life)	Baseline, Time 2, Time 3

Other

Measure	Time frame
Exercise Assessment	Baseline, Time 2, and Time 3

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 9, 2026