Esophageal Cancer
Conditions
Keywords
Nutritional Disorders, Feeding Behavior
Brief summary
Esophagectomy for cancer is often accompanied with severe preoperative weight loss. Body Mass Index (BMI) values are age-independent and the same for both sexes. From the perspective that these two parameters should actually be taken into account too, we developed a model to calculate age-gender specific BMI-percentiles (AG-BMI) and tested this model in relation to survival outcome after esophagectomy for cancer.
Detailed description
Age-Gender specific BMI percentiles are more accurate compared to the current BMI classes in predicting Overall Survival (OS) after esophagectomy for cancer. Furthermore we believe in a more devastating impact on OS from underweight and not from overweight. By preoperatively identifying risk patients for poorer OS, especially the non-tumoral deaths, this can be a tool to tailor postoperative nutritional strategies to counter further weight loss and bringing postoperative weight to normal ranges.
Interventions
None listed
Sponsors
University Hospital, Gasthuisberg
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 95 Years
Healthy volunteers
No
Inclusion criteria
* any type of esophagectomy
Exclusion criteria
* Preoperative organ metastasis (cM+ or yM+) * esophageal bypass surgery
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Overall 5 year survival | 5 years after esophagectomy | Overall 5-year survival after esophagectomy for cancer |
Countries
Belgium
Outcome results
None listed